Evidence map›Paper›PMID 38847347›Full record

ArticleClinical and translational science2024

Pharmacokinetics of single-dose rivaroxaban under fed state in obese vs. non-obese subjects: An open-label controlled clinical trial (RIVOBESE-PK).

Majdoleen Alalawneh, Ahmed Awaisu, Ibtihal Abdallah, Hazem Elewa, Mohammed Danjuma, Kamal M Matar, Akram M ElKashlan, Yasser Elshayep, Fathy Ibrahim, Ousama Rachid

Abstract readControlled Clinical TrialComparative Study
In one paragraph

Article in Clinical and translational science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Majdoleen AlalawnehCollege of Pharmacy, Health Sector, Qatar University, Doha, Qatar.ORCID 0000-0002-6597-1647
Ahmed AwaisuCollege of Pharmacy, Health Sector, Qatar University, Doha, Qatar.ORCID 0000-0002-9029-8925
Ibtihal AbdallahInternal Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.ORCID 0000-0001-7151-6280
Hazem ElewaCollege of Pharmacy, Health Sector, Qatar University, Doha, Qatar.ORCID 0000-0003-1594-1199
Mohammed DanjumaInternal Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.ORCID 0000-0003-2198-5278
Kamal M MatarDepartment of Pharmacology & Therapeutics, Faculty of Pharmacy, Kuwait University, Kuwait City, Kuwait.ORCID 0000-0002-2854-980X
Akram M ElKashlanDepartment of Biochemistry, Faculty of Pharmacy, University of Sadat City, Sadat City, Egypt.ORCID 0000-0002-5261-8043
Yasser ElshayepInternational Center for Bioavailability, Pharmaceutical, and Clinical Research, Cairo, Egypt.ORCID 0009-0004-7783-2646
Fathy IbrahimInternational Center for Bioavailability, Pharmaceutical, and Clinical Research, Cairo, Egypt.ORCID 0000-0003-3522-0671
Ousama RachidCollege of Pharmacy, Health Sector, Qatar University, Doha, Qatar.ORCID 0000-0002-2364-3848

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evidence of rivaroxaban's pharmacokinetics in obese compared with non-obese populations remains inconclusive. We aimed to compare the pharmacokinetic profile of rivaroxaban between obese and non-obese populations under fed state. Participants who met the study's eligibility criteria were assigned into one of two groups: obese (body mass index ≥35 kg/m

Indexed as

Factor Xa InhibitorsObesityRivaroxabanAdministration, OralAdultArea Under CurveBody Mass IndexFemaleHalf-LifeHumansMaleMiddle AgedYoung AdultFactor Xa InhibitorsRivaroxaban

Identifiers

PMID38847347
PMCPMC11157419

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.