Evidence map›Paper›PMID 38847308›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2024

Exploring of N-phthalimide-linked 1,2,3-triazole analogues with promising -anti-SARS-CoV-2 activity: synthesis, biological screening, and molecular modelling studies.

Ateyatallah Aljuhani, Mosa Alsehli, Mohamed A Seleem, Shaya Y Alraqa, Hany E A Ahmed, Nadjet Rezki, Mohamed R Aouad

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ateyatallah AljuhaniChemistry Department, College of Sciences, Taibah University, Saudi Arabia.
Mosa AlsehliChemistry Department, College of Sciences, Taibah University, Saudi Arabia.
Mohamed A SeleemPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Nasr, City, Cairo, Egypt.
Shaya Y AlraqaChemistry Department, College of Sciences, Taibah University, Saudi Arabia.
Hany E A AhmedPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Nasr, City, Cairo, Egypt.ORCID 0000-0001-8898-8452
Nadjet RezkiChemistry Department, College of Sciences, Taibah University, Saudi Arabia.ORCID 0000-0001-8330-1738
Mohamed R AouadChemistry Department, College of Sciences, Taibah University, Saudi Arabia.ORCID 0000-0001-7018-6654

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a library of phthalimide Schiff base linked to 1,4-disubstituted-1,2,3-triazoles was designed, synthesised, and characterised by different spectral analyses. All analogues have been introduced for

Indexed as

Antiviral AgentsMolecular Docking SimulationPhthalimidesSARS-CoV-2TriazolesAnimalsChlorocebus aethiopsCoronavirus 3C ProteasesDose-Response Relationship, DrugHumansMicrobial Sensitivity TestsModels, MolecularMolecular StructureStructure-Activity RelationshipVero CellsAntiviral AgentsCoronavirus 3C ProteasesphthalimidePhthalimidesTriazoles123-TriazoleCOVID-19molecular dockingphtalamideSchiff bases

Identifiers

PMID38847308
PMCPMC11164105

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.