Evidence map›Paper›PMID 38847239›Full record

ArticleEquine veterinary journal2025

Yearling laryngeal function in Thoroughbreds that underwent a laryngoplasty differs from controls.

Josephine L Hardwick, Benjamin J Ahern, Kylie L Crawford, Kate J Allen, Samantha H Franklin

Abstract read
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Article in Equine veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Josephine L HardwickSchool of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, South Australia, Australia.ORCID https://orcid.org/0000-0001-7537-9041
Benjamin J AhernSchool of Veterinary Science, University of Queensland, Gatton, Queensland, Australia.ORCID https://orcid.org/0000-0001-5527-8964
Kylie L CrawfordMater Research Institute, University of Queensland, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-9403-0096
Kate J AllenSchool of Veterinary Sciences, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0002-3045-1238
Samantha H FranklinSchool of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, South Australia, Australia.ORCID https://orcid.org/0000-0002-6761-5371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundYearling laryngeal function (YLF) is frequently assessed at the time of sale and the outcomes of these assessments can have significant economic implications. The YLF of horses that subsequently underwent a prosthetic laryngoplasty (PL) is unknown.

objectivesWe hypothesised horses with YLF ≥grade II.2 would be at increased risk of requiring PL, compared with YLF <grade II.2. STUDY

designCase-control.

methodsThere were 150 PL cases from 2019 to 2021 with an available yearling post-sale videoendoscopic examination and 600 controls. Two observers unaware of the outcome graded YLF using the Havemeyer system. The risk of PL for each YLF grade was calculated using multivariable conditional logistic regression.

resultsThe proportions of each YLF grade in the control group and PL group, respectively, were grade I: 25.8% and 13.3%, grade II.1: 54.3% and 35.3%, grade II.2: 16.7% and 26%, grade III.1: 3% and 20.7%, grade III.2: 0.2% and 3.3%, grade III.3: 0% and 0.7%, grade IV: 0% and 0.7%. The odds ratio (OR, 95% confidence interval) of requiring PL compared with the referent grade I were: grade II.1: 1.2 (0.7, 2.2, p = 0.5), grade II.2: 3.4 (1.8, 6.1, p < 0.001), grade III.1: 13.8 (6.0, 31.6, p < 0.001), grade III.2: 55.5 (10.3, 299.2, p < 0.001), grade III.3: 2930,000 (398173.7, 21 600,000, p < 0.001), grade IV: 26300,000 (3 420 000, 202 000 000, p < 0.001). Yearling LF ≥grade II.2 had an OR of 4.61 (3.0, 7.1, p < 0.001) compared with <grade II.2; YLF ≥grade III.1 had an OR of 10.7 (5.6, 20.4, p < 0.001) compared with <grade III.1. MAIN LIMITATIONS: Lack of performance data to compare the PL and control groups. The control group was not 'disease-free' and may have developed disease and been retired or undergone surgery elsewhere.

conclusionsThree-quarters of the PL group had ≤grade II.2 YLF, demonstrating deterioration in LF post-sale was common. The risk of requiring PL increased from YLF grade II.2 upwards.

Indexed as

Horse DiseasesLaryngeal DiseasesLaryngoplastyLarynxVocal Cord ParalysisAnimalsCase-Control StudiesFemaleHorsesMalehorselarynxsalesurgeryupper airway

Identifiers

PMID38847239
PMCPMC11807936

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.