Evidence map›Paper›PMID 38847116›Full record

ReviewCytometry. Part A : the journal of the International Society for Analytical Cytology2024

Deciphering the aging process through single-cell cytometric technologies.

Lok Ming Tam, Timothy Bushnell

Abstract readReview
In one paragraph

Review in Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lok Ming TamCenter for Advanced Research Technologies, University of Rochester Medical Center, Rochester, New York, USA.ORCID 0000-0002-6211-6880
Timothy BushnellCenter for Advanced Research Technologies, University of Rochester Medical Center, Rochester, New York, USA.ORCID 0000-0002-5060-0122

Funding

Rochester Partnership to Advance Research and Academic Careers in Deaf ScholarsK12GM106997 · NIGMS · UNIVERSITY OF ROCHESTER · PI BUCKLEY, GERARD J., DEWHURST, STEPHEN · 2015 to 2024
$6.9M
Institutional FundingNIGMS NIH HHS K12 GM106997NIGMS NIH HHS K12GM106997
6 · The paper itself

Abstract

The advent of single-cell cytometric technologies, in conjunction with advances in single-cell biology, has significantly propelled forward the field of geroscience, enhancing our comprehension of the mechanisms underlying age-related diseases. Given that aging is a primary risk factor for numerous chronic health conditions, investigating the dynamic changes within the physiological landscape at the granularity of single cells is crucial for elucidating the molecular foundations of biological aging. Utilizing hallmarks of aging as a conceptual framework, we review current literature to delineate the progression of single-cell cytometric techniques and their pivotal applications in the exploration of molecular alterations associated with aging. We next discuss recent advancements in single-cell cytometry in terms of the development in instrument, software, and reagents, highlighting its promising and critical role in driving future breakthrough discoveries in aging research.

Indexed as

AgingFlow CytometrySingle-Cell AnalysisAnimalsCellular SenescenceHumans

Identifiers

PMID38847116
PMCPMC12147454

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.