ReviewThe International journal of angiology : official publication of the International College of Angiology, Inc2024
Epidemiology, Etiology, and Pathophysiology of Pulmonary Embolism.
Review in The International journal of angiology : official publication of the International College of Angiology, Inc, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Catheter-directed thrombolysis versus anticoagulation for intermediate-risk and high-risk pulmonary embolism: a systematic review and meta-analysis.Open heart · 2026Pooled it
- Interventional Management of Intermediate-High-Risk Pulmonary Embolism: Current Evidence, Patient Selection and Personalised Treatment Strategies.Journal of clinical medicine · 2026Review
- Optimizing CT pulmonary angiography with patient-adaptive triggering-a novel approach for a "one-stop-shop" evaluation of pulmonary and aortic vasculature.European radiology · 2026Article
- Imaging-Driven Risk Stratification and Endovascular Decision Pathways in Acute Pulmonary Embolism.Diagnostics (Basel, Switzerland) · 2026Review
- Evaluating the Predictive Value of the Endothelial Activation and Stress Index in Determining the Severity and Prognosis of Acute Pulmonary Embolism.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2026Article
- Aortic pseudoaneurysm caused by Tempofilter II inferior vena cava filter strut perforation: a case report.Frontiers in surgery · 2026Article
- Predictors of right ventricular dysfunction and its clinical value after reperfusion of acute right coronary artery occlusion: a single-center retrospective analysis.American journal of translational research · 2026Article
- Ultrasound Images That Speak: Assessing the Therapeutic Decision in the Emergency Department Regarding the Risk-Benefit Ratio of Systemic Thrombolysis in Intermediate-High-Risk Pulmonary Embolism-A Case Report.Diagnostics (Basel, Switzerland) · 2025Article
- Global trends in mortality related to pulmonary embolism: an epidemiological analysis of data from the World Health Organization mortality database from 2001 to 2023.EClinicalMedicine · 2025Article
- A Direct Relationship Between 'Blood Stasis' and Fibrinaloid Microclots in Chronic, Inflammatory, and Vascular Diseases, and Some Traditional Natural Products Approaches to Treatment.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Risk factors for pulmonary embolism: a case-control study.Journal of thoracic disease · 2025Article
- Successful Endovascular Management of Concomitant Ischemic Stroke, Myocardial Infarction, and Massive Pulmonary Embolism.JACC. Case reports · 2025Article
- Dyspnea after a first episode of pulmonary embolism: prevalence, predictors and long-term associations with health-related quality of life.Frontiers in cardiovascular medicine · 2025Article
- Correlation between decreased PaCOFrontiers in medicine · 2025Article
- A novel predictor of short-term prognosis in acute pulmonary embolism: inflammatory burden index.Therapeutic advances in cardiovascular diseaseArticle
- Mortality trends in the United States for adults with concurrent cerebrovascular disease and pulmonary embolism.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last 20 years, there has been a progressive increase in the incidence of pulmonary embolism (PE) diagnosis in the United States, Europe, and Australia. Increased use of computed tomography pulmonary angiography has likely contributed in part to this rising incidence. However, it is pertinent to note that the burden of comorbidities associated with PE, such as malignancy, obesity, and advanced age, has also increased over the past 20 years. Time-trend analysis in North American, European, and Asian populations suggests that mortality rates associated with PE have been declining. The reported improved survival rates in PE over the past 20 years are likely, at least in part, to be the result of better adherence to guidelines, improved risk stratification, and enhanced treatment. Factors contributing to the development of venous thromboembolism (VTE) include stasis of blood, hypercoagulability, endothelial injury, and inflammation. In 70 to 80% of cases of PE, the thrombi embolizes from the proximal deep veins of the lower extremities and pelvis. Strong risk factors for VTE include lower extremity fractures and surgeries, major trauma, and hospitalization within the previous 3 months for acute myocardial infarction or heart failure with atrial fibrillation. Acute PE causes several pathophysiological responses including hypoxemia and right ventricle (RV) failure. The latter is a result of pulmonary artery occlusion and associated vasoconstriction. Hemodynamic compromise from RV failure is the principal cause of poor outcome in patients with acute PE.
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