Evidence map›Paper›PMID 38846908›Full record

ArticleMuscles (Basel, Switzerland)2024

Sarcopenia Identification Using Alternative Vertebral Landmarks in Individuals with Lung Cancer.

Cecily A Byrne, Giamila Fantuzzi, Jeremy T Stephan, Sage Kim, Vanessa M Oddo, Timothy J Koh, Sandra L Gomez

Abstract read
In one paragraph

Article in Muscles (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Future of CT body composition research: Methodological discrepancies and advances.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cecily A ByrneCancer Health Equity and Career Development Program, University of Illinois Chicago, 1747 W. Roosevelt Rd., Chicago, IL 60608, USA.ORCID 0000-0002-8130-5927
Giamila FantuzziDepartment of Kinesiology and Nutrition, University of Illinois Chicago, 1919 W. Taylor St., Chicago, IL 60612, USA.
Jeremy T StephanDepartment of Radiology, Rush University Medical Center, 1653 W. Congress Parkway, Chicago, IL 60612, USA.
Sage KimSchool of Public Health, University of Illinois Chicago, 1603 W. Taylor St., Chicago, IL 60612, USA.ORCID 0000-0001-8939-5157
Vanessa M OddoDepartment of Kinesiology and Nutrition, University of Illinois Chicago, 1919 W. Taylor St., Chicago, IL 60612, USA.ORCID 0000-0002-8893-0637
Timothy J KohDepartment of Kinesiology and Nutrition, University of Illinois Chicago, 1919 W. Taylor St., Chicago, IL 60612, USA.ORCID 0000-0001-6549-7060
Sandra L GomezDepartment of Clinical Nutrition, Rush University, 600 S. Paulina St., Chicago, IL 60612, USA.

Funding

UIC CANCER PREVENTION &CONTROL RESEARCH TRAINING GRANTR25CA057699 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FITZGIBBON, MARIAN L. · 1992 to 2017
$8.2M
Cancer Health Equity Career Development ProgramT32CA057699 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Marian L. Fitzgibbon · 2018 to 2026
$3.0M
NCI NIH HHS R25 CA057699NCI NIH HHS T32 CA057699
6 · The paper itself

Abstract

Background: (1)Sarcopenia, or low skeletal mass index (SMI), contributes to higher lung cancer mortality. The SMI at third lumbar vertebrae (L3) is the reference standard for body composition analysis. However, there is a need to explore the validity of alternative landmarks in this population. We compared the agreement of sarcopenia identification at the first lumbar (L1) and second lumbar (L2) to L3 in non-Hispanic Black (NHB) and White (NHW) individuals with lung cancer. Methods: (2)This retrospective, cross-sectional study included 214 NHB and NHW adults with lung cancer. CT scans were analyzed to calculate the SMI at L1, L2, and L3. T-tests, chi-square, Pearson's correlation, Cohen's kappa, sensitivity, and specificity analysis were used. Results: (3)Subjects presented with a mean age of 68.4 ± 9.9 years and BMI of 26.3 ± 6.0 kg/m Conclusions: (4)Sarcopenia prevalence varied greatly depending on the vertebral landmark used for assessment. Using L2 or L1 alone resulted in a 16.8% and 23.8% misclassification of sarcopenia in this cohort of individuals with lung cancer.

Indexed as

agreementalternative vertebral landmarkslung cancersarcopenia

Identifiers

PMID38846908
PMCPMC11155469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.