ArticleFrontiers in public health2024
Association between urinary metals and prostate-specific antigen in aging population with depression: a cross-sectional study.
Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Joint effects of sleep duration and sleep difficulty on suicidal ideation: evidence from NHANES 2005-2018.BMC psychiatry · 2026Article
- Relationship between BMI, indicators of lipid metabolism and diabetic neuropathy: a Mendelian randomization study.Diabetology & metabolic syndrome · 2025Article
- Global, regional and country-specific burden of patella, tibia or fibula, or ankle fractures and its prediction to 2035: findings from global burden of disease study 2019.BMC public health · 2024Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to investigate the impact of depression and urinary metals on Prostate-Specific Antigen (PSA). Methods: Analysis was conducted on 1901 samples collected from the National Health and Nutrition Examination Survey (NHANES) database between 2001 and 2010. Analytical methods included stepwise multiple linear regression (MLR) analysis of the overall population's urinary metals and PSA relationship, analysis of urinary metals and PSA relationship in older adults and BMI subgroups, analysis of urinary metals and PSA relationship in the depressed population, and restricted cubic spline (RCS) analysis. A significance level of Results: In the stepwise multiple linear regression, beryllium (Be) showed a dose-response association with PSA (third quartile: β = 0.05, 95%CI (0.02, 0.09); fourth quartile: β = 0.07, 95%CI (0.02, 0.12), Conclusion: Individuals exposed to beryllium (Be), especially the older adults and overweight, should monitor their PSA levels. In depressed patients, cadmium (Cd) levels may further elevate PSA levels, necessitating increased monitoring of PSA levels among males.
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