ArticleFrontiers in endocrinology2024
Correlation of TyG-BMI and TyG-WC with severity and short-term outcome in new-onset acute ischemic stroke.
Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Association between the cumulative average triglyceride-glucose-waist circumference index and new-onset hypertension among Chinese middle-aged and older adults-a national prospective study.Cardiovascular diabetology. Endocrinology reports · 2026Article
- Observational
- Sex-Specific Associations of Triglyceride-Glucose Index and a Body Shape Index with Cardiometabolic Multimorbidity Risk: A Prospective Cohort Study.Journal of clinical medicine · 2026Article
- Machine learning evaluation of TyG-based metrics for arteriosclerosis progression.Scientific reports · 2026Article
- Anthropometry-adjusted TyG indices improve insulin resistance estimation: an exploratory euglycemic-hyperinsulinemic clamp study in Japanese adults without diabetes.Diabetology international · 2026Article
- Simplicity meets accuracy: TyG-Waist as a practical alternative to CVAI for type 2 diabetes prediction in high-risk Chinese adults.BMC endocrine disorders · 2026Article
- Comparison of TyG indices and atherogenic index of plasma with hypertension in the PERSIAN Guilan cohort.Scientific reports · 2026Article
- Association of estimated glucose disposal rate and body mass index with stroke risk in middle-aged and elderly populations: evidence from two cohort studies.BMC neurology · 2026Article
- Association of the single point insulin sensitivity estimator index with functional outcomes and hemorrhagic transformation in patients with acute ischemic stroke.Frontiers in nutrition · 2026Article
- The interactive effect of sex and neutrophil-to-lymphocyte ratio on short-term poor outcomes in patients with nonvalvular atrial fibrillation-related acute cardioembolic stroke.European journal of medical research · 2025Article
- The triglyceride-glucose index: updating evidence from clinical settings to molecular mechanisms in ageing-related cerebrovascular diseases.Cardiovascular diabetology · 2025Review
- Associations of the Neutrophil-to-Lymphocyte Ratio(NLR), Triglyceride-Glucose Index (TyG), and TyG-derived indices with vitality decline in older adults in China: a study within the Integrated Care for Older People (ICOPE) framework.Lipids in health and disease · 2025Article
- Association between modified triglyceride glucose indices and stroke risk in middle-aged and older Chinese adults: a prospective cohort study.Cardiovascular diabetology · 2025Article
- Article
- Comparison of Ischemic Stroke Outcomes in Patients With and Without Metabolic Syndrome: A Systematic Review.Cureus · 2025Review
- Association between the triglyceride glucose body mass index and asthma: evidence from NHANES 2011-2018.BMC pulmonary medicine · 2025Article
- A comprehensive analysis of stroke risk factors and development of a predictive model using machine learning approaches.Molecular genetics and genomics : MGG · 2025Article
- Research status of triglyceride glucose-body mass index (TyG-BMI index).Frontiers in cardiovascular medicine · 2025Review
- Correlation of the triglyceride-glucose-body mass index with all-cause and cardiovascular mortality in patients undergoing peritoneal dialysis: a retrospective cohort study.Frontiers in nutrition · 2025Article
- Nomogram Models Integrating TyG Index for Predicting Early Neurological Deterioration and 90-Day Outcomes in AIS Patients Undergoing IVT.Journal of central nervous system disease · 2025Article
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7 authors.
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Abstract
Objectives: To research the connection between the indexes of the indexes of triglyceride-glucose (TyG) combined with obesity indices and the initial neurological severity and short-term outcome of new-onset acute ischemic stroke. Methods: Data of patients with acute ischemic stroke admitted to the Stroke Ward of the Affiliated Hospital of Beihua University from November 2021 to October 2023, were collected. The two indexes were calculated by combining TyG and obesity indices: TyG-body mass index (TyG-BMI) and TyG-waist circumference (TyG-WC). The National Institute of Health Stroke Scale (NIHSS) was used to assess and group patients with neurological deficits within 24 hours of admission: mild stroke (NIHSS ≤5) and moderate-severe stroke (NIHSS >5). Short-term prognosis was evaluated using the modified Rankin Scale (mRS) at discharge or 14 days after onset of the disease and grouped: good outcome (mRS ≤2) and poor outcome (mRS >2). According to the quartiles of TyG-BMI and TyG-WC, the patients were placed into four groups: Q1, Q2, Q3 and Q4. Multi-factor logistic regression analysis was utilized to evaluate the correlation of TyG-BMI and TyG-WC with the severity and short-term outcome. Results: The study included 456 patients. After adjusting for multiple variables, the results showed that compared with the quartile 1, patients in quartile 4 of TyG-BMI had a reduced risk of moderate-severe stroke [Q4: OR: 0.407, 95%CI (0.185-0.894), P = 0.025]; Patients in quartiles 2, 3 and 4 of TyG-BMI had sequentially lower risk of short-term adverse outcomes [Q2: OR: 0.394, 95%CI (0.215-0.722), P = 0.003; Q3: OR: 0.324, 95%CI (0.163-0.642), P = 0.001; Q4: OR: 0.158, 95%CI (0.027-0.349), P <0.001]; Patients in quartiles 3 and 4 of TyG-WC had sequentially lower risk of moderate-severe stroke [Q3: OR: 0.355, 95%CI (0.173-0.728), P = 0.005; Q4: OR: 0.140, 95%CI (0.056-0.351), P <0.001]; Patients in quartiles 3 and 4 of TyG-WC had sequentially lower risk of short-term adverse outcomes [Q3: OR: 0.350, 95%CI (0.175-0.700), P = 0.003; Q4: OR: 0.178, 95%CI (0.071-0.451), P <0.001]. Conclusions: TyG-WC and TyG-BMI were correlated with the severity and short-term outcome of new-onset acute ischemic stroke. As TyG-WC and TyG-BMI increased, stroke severity decreased and short-term outcome was better.
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