Evidence map›Paper›PMID 38846376›Full record

ArticleFASEB bioAdvances2024

The effects of oxidative stress and intracellular calcium on mitochondrial permeability transition pore formation in equine spermatozoa.

Zamira Gibb, Robert J Aitken, Alecia R Sheridan, Brandan Holt, Stephanie Waugh, Aleona Swegen

Abstract read
In one paragraph

Article in FASEB bioAdvances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zamira GibbSchool of Environmental and Life Sciences, College of Engineering, Science and Environment The University of Newcastle Callaghan New South Wales Australia.ORCID https://orcid.org/0000-0002-4864-8880
Robert J AitkenSchool of Environmental and Life Sciences, College of Engineering, Science and Environment The University of Newcastle Callaghan New South Wales Australia.ORCID https://orcid.org/0000-0002-9152-156X
Alecia R SheridanSchool of Environmental and Life Sciences, College of Engineering, Science and Environment The University of Newcastle Callaghan New South Wales Australia.ORCID https://orcid.org/0009-0006-3814-9734
Brandan HoltFaculty of Health, School of Biomedical Sciences Queensland University of Technology Brisbane Queensland Australia.ORCID https://orcid.org/0009-0001-2560-085X
Stephanie WaughSchool of Environmental and Life Sciences, College of Engineering, Science and Environment The University of Newcastle Callaghan New South Wales Australia.ORCID https://orcid.org/0000-0002-2125-2288
Aleona SwegenSchool of Environmental and Life Sciences, College of Engineering, Science and Environment The University of Newcastle Callaghan New South Wales Australia.ORCID https://orcid.org/0000-0001-7371-5400

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The in vitro storage of stallion spermatozoa for use in artificial insemination leads to oxidative stress and imbalances in calcium homeostasis that trigger the formation of the mitochondrial permeability transition pore (mPTP), resulting in premature cell death. However, little is understood about the dynamics and the role of mPTP formation in mammalian spermatozoa. Here, we identify an important role for mPTP in stallion sperm Ca

Indexed as

horseJC‐1mitochondrial permeability transition poreoxidative stressspermatozoa

Identifiers

PMID38846376
PMCPMC11150759

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.