Evidence map›Paper›PMID 38846361›Full record

ArticleChina CDC weekly2024

Exploration for the Priority of HIV Intervention: Modelling Health Impact and Cost-Effectiveness - Six Cities, Eastern China, 2019-2028.

Youran Zhang, Lili Wang, Zhen Jiang, Hongjing Yan, Xiaoxia Liu, Jing Gu, Guoyong Wang, Xiaosong Cheng, Qiyan Leng, Qisui Long and 6 more

Abstract read
In one paragraph

Article in China CDC weekly, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Youran ZhangSchool of Health Service Management, Anhui Medical University, Hefei City, Anhui Province, China.
Lili WangSchool of Health Service Management, Anhui Medical University, Hefei City, Anhui Province, China.
Zhen JiangDivision of Prevention and intervention, National Center for AIDS and STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Hongjing YanJiangsu Provincial Center for Disease Control and Prevention, Nanjing City, Jiangsu Province, China.
Xiaoxia LiuZhenjiang Center for Disease Control and Prevention, Zhenjiang City, Jiangsu Province, China.
Jing GuWuxi Center for Disease Control and Prevention, Wuxi City, Jiangsu Province, China.
Guoyong WangShandong Provincial Center for Disease Control and Prevention, Jinan City, Shandong Province, China.
Xiaosong ChengYantai Center for Disease Control and Prevention, Yantai City, Shandong Province, China.
Qiyan LengYantai Center for Disease Control and Prevention, Yantai City, Shandong Province, China.
Qisui LongGuangdong Provincial Center for Disease Control and Prevention, Guangzhou City, Guangdong Province, China.
Zimian LiangFoshan Center for Disease Control and Prevention, Foshan City, Guangdong Province, China.
Jing WangFoshan Center for Disease Control and Prevention, Foshan City, Guangdong Province, China.
Liang LiangHebei Provincial Center for Disease Control and Prevention, Shijiazhuang City, Hebei Province, China.
Yanchao QiuShijiazhuang Center for Disease Control and Prevention, Shijiazhuang City, China.
Lin ChenZhejiang Provincial Center for Disease Control and Prevention, Hangzhou City, Zhejiang Province, China.
Hang HongNingbo Center for Disease Control and Prevention, Ningbo City, Zhejiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In order to enhance the effectiveness of resource allocation, regions must tailor their responses to their specific epidemiological and economic situations. Methods: Utilizing Spectrum software, we projected the cost-effectiveness of 10 chosen HIV interventions in six cities in eastern China from 2019 to 2028. We assessed three scenarios - Base, Achievable, and Idealized - for each city. The analysis included the projected number of HIV infections and deaths averted, as well as the incremental cost-effectiveness ratios for each intervention in the six cities. Results: In Shijiazhuang, Wuxi, Yantai, and Zhenjiang, cities with initially low antiretroviral therapy (ART) coverage, ART showed significant effectiveness, especially for males. Conversely, in Foshan and Ningbo, where ART coverage was notably high, oral pre-exposure prophylaxis (PrEP) for men who have sex with men (MSM) proved effective in the Idealized scenario. MSM outreach, ART for males, and ART for females demonstrated cost-effectiveness across all six cities in both Achievable and Idealized scenarios at the predefined thresholds for each city. Discussion: Maintaining an appropriate coverage rate for outreach to MSM can lead to cost-effectiveness. In cities with low ART coverage, scaling up ART remains a crucial intervention. In regions with high ART coverage, consideration may be given to the utilization of oral PrEP for MSM individuals, requiring budget allocation.

Indexed as

cost-effectivenesseastern ChinaHIV interventionSpectrum

Identifiers

PMID38846361
PMCPMC11150166

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.