Evidence map›Paper›PMID 38846093›Full record

ArticleFrontiers in pharmacology2024

Fragment-based virtual screening identifies novel leads against Plasmepsin IX (PlmIX) of

Haider Thaer Abdulhameed Almuqdadi, Sumaiya Kifayat, Razique Anwer, Jihad Alrehaili, Mohammad Abid

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haider Thaer Abdulhameed AlmuqdadiMedicinal Chemistry Laboratory, Department of Biosciences, Jamia Millia Islamia, New Delhi, India.
Sumaiya KifayatMedicinal Chemistry Laboratory, Department of Biosciences, Jamia Millia Islamia, New Delhi, India.
Razique AnwerDepartment of Pathology, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Jihad AlrehailiDepartment of Pathology, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Mohammad AbidMedicinal Chemistry Laboratory, Department of Biosciences, Jamia Millia Islamia, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite continuous efforts to develop safer and efficient medications, malaria remains a major threat posing great challenges for new drug discovery. The emerging drug resistance, increased toxicities, and impoverished pharmacokinetic profiles exhibited by conventional drugs have hindered the search for new entities. Plasmepsins, a group of

Indexed as

antimalarialsfragment-based drug designhomology modelingmolecular dockingmolecular docking simulationPlasmepsin IX

Identifiers

PMID38846093
PMCPMC11153788

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.