Evidence map›Paper›PMID 38846065›Full record

ArticleEnvironmental epigenetics2024

Accelerated aging and altered subclinical response to ozone exposure in young, healthy adults.

William C Weston, Marie Abèle Bind, Wayne E Cascio, Robert B Devlin, David Diaz-Sanchez, Cavin K Ward-Caviness

Abstract read
In one paragraph

Article in Environmental epigenetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William C WestonCenter for Public Health and Environmental Assessment, US Environmental Protection Agency, Chapel Hill, NC 27514, USA.
Marie Abèle BindBiostatistics Center, Massachusetts General Hospital, Boston, MA 02114, USA.
Wayne E CascioCenter for Public Health and Environmental Assessment, US Environmental Protection Agency, Chapel Hill, NC 27514, USA.ORCID https://orcid.org/0000-0003-1360-8093
Robert B DevlinCenter for Public Health and Environmental Assessment, US Environmental Protection Agency, Chapel Hill, NC 27514, USA.ORCID https://orcid.org/0000-0002-8510-2000
David Diaz-SanchezCenter for Public Health and Environmental Assessment, US Environmental Protection Agency, Chapel Hill, NC 27514, USA.
Cavin K Ward-CavinessCenter for Public Health and Environmental Assessment, US Environmental Protection Agency, Chapel Hill, NC 27514, USA.ORCID https://orcid.org/0000-0002-6322-4349

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ozone exposure induces a myriad of adverse cardiopulmonary outcomes in humans. Although advanced age and chronic disease are factors that may exacerbate a person's negative response to ozone exposure, there are no molecular biomarkers of susceptibility. Here, we examine whether epigenetic age acceleration (EAA) is associated with responsiveness to short-term ozone exposure. Using data from a crossover-controlled exposure study (

Indexed as

accelerated agingenvironmental susceptibilityepigenetic agingozone

Identifiers

PMID38846065
PMCPMC11155485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.