Evidence map›Paper›PMID 38845815›Full record

ReviewEngineering in life sciences2024

Current trends in medium-chain-length polyhydroxyalkanoates: Microbial production, purification, and characterization.

Thomas Hahn, Melissa Ortega Alzate, Steven Leonhardt, Pravesh Tamang, Susanne Zibek

Abstract readReview
In one paragraph

Review in Engineering in life sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas HahnBioprocess Development Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB Stuttgart Germany.ORCID https://orcid.org/0000-0001-8428-0342
Melissa Ortega AlzateBioprocess Development Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB Stuttgart Germany.
Steven LeonhardtBioprocess Development Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB Stuttgart Germany.
Pravesh TamangBioprocess Development Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB Stuttgart Germany.ORCID https://orcid.org/0000-0002-5994-0254
Susanne ZibekBioprocess Development Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB Stuttgart Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyhydroxyalkanoates (PHAs) have gained interest recently due to their biodegradability and versatility. In particular, the chemical compositions of medium-chain-length (mcl)-PHAs are highly diverse, comprising different monomers containing 6-14 carbon atoms. This review summarizes different feedstocks and fermentation strategies to enhance mcl-PHA production and briefly discusses the downstream processing. This review also provides comprehensive details on analytical tools for determining the composition and properties of mcl-PHA. Moreover, this study provides novel information by statistically analyzing the data collected from several reports on mcl-PHA to determine the optimal fermentation parameters (specific growth rate, PHA productivity, and PHA yield from various structurally related and unrelated substrates), mcl-PHA composition, molecular weight (MW), and thermal and mechanical properties, in addition to other relevant statistical values. The analysis revealed that the median PHA productivity observed in the fed-batch feeding strategy was 0.4 g L

Indexed as

biopolymerdownstream processingmedium‐chain‐lengthpolyhydroxyalkanoatethermal and mechanical properties

Identifiers

PMID38845815
PMCPMC11151071

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.