Evidence map›Paper›PMID 38845796›Full record

ArticleEuropean heart journal. Imaging methods and practice2024

CMR characterization of patients with heart failure and left bundle branch block.

Raluca Tomoaia, Peter Harrison, Lydia Bevis, Ali Wahab, Patrick Thompson, Christopher E D Saunderson, Eylem Levelt, Erica Dall'Armellina, Pankaj Garg, John P Greenwood and 2 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal. Imaging methods and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Raluca TomoaiaBiomedical Imaging Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse, Leeds, West Yorkshire LS2 9JT, UK.ORCID https://orcid.org/0000-0002-1944-4088
Peter HarrisonBiomedical Imaging Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse, Leeds, West Yorkshire LS2 9JT, UK.
Lydia BevisBiomedical Imaging Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse, Leeds, West Yorkshire LS2 9JT, UK.
Ali WahabBiomedical Imaging Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse, Leeds, West Yorkshire LS2 9JT, UK.
Patrick ThompsonBiomedical Imaging Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse, Leeds, West Yorkshire LS2 9JT, UK.
Christopher E D SaundersonBiomedical Imaging Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse, Leeds, West Yorkshire LS2 9JT, UK.
Eylem LeveltBiomedical Imaging Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse, Leeds, West Yorkshire LS2 9JT, UK.
Erica Dall'ArmellinaBiomedical Imaging Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse, Leeds, West Yorkshire LS2 9JT, UK.
Pankaj GargDepartment of Cardiovascular and Metabolic Health, Norwich Medical School, University of East Anglia, Norfolk, UK.
John P GreenwoodBiomedical Imaging Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse, Leeds, West Yorkshire LS2 9JT, UK.
Sven PleinBiomedical Imaging Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse, Leeds, West Yorkshire LS2 9JT, UK.ORCID https://orcid.org/0000-0002-0997-4384
Peter P SwobodaBiomedical Imaging Sciences Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Woodhouse, Leeds, West Yorkshire LS2 9JT, UK.ORCID https://orcid.org/0000-0001-7162-7079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: We aimed to identify the distinctive cardiovascular magnetic resonance (CMR) features of patients with left bundle branch block (LBBB) and heart failure with reduced ejection fraction (HFrEF) of presumed non-ischaemic aetiology. The secondary aim was to determine whether these individuals exhibit characteristics that could potentially serve as predictors of left ventricular ejection fraction (LVEF) recovery as compared with patients without LBBB. Methods and results: We prospectively recruited patients with HFrEF (LVEF ≤ 40%) on echocardiography who were referred for early CMR examination. Patients with an established diagnosis of coronary artery disease and known structural or congenital heart disease were excluded. LV recovery was defined as achieving ≥10% absolute improvement to ≥40% in LVEF between baseline evaluation to CMR. A total of 391 patients were recruited including 115 (29.4%) with LBBB. Compared with HF patients without LBBB, those with LBBB exhibited larger left ventricles and smaller right ventricles, but no differences were observed with respect to LVEF (35.8 ± 12 vs. 38 ± 12%, Conclusion: Patients presenting with HFrEF and LBBB had larger LV cavities and smaller RV cavities than those without LBBB but no difference in prevalence of scar or ischaemia. The rates of LV recovery were similar between both groups, which supports current guidelines to defer device therapy until 3-6 months of guideline-directed medical therapy, rather than early CMR and device implantation.

Indexed as

heart failureleft bundle branch blockmagnetic resonance imaging

Identifiers

PMID38845796
PMCPMC11151275

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.