Evidence map›Paper›PMID 38845791›Full record

ArticleTherapeutic advances in medical oncology2024

Diagnosis and treatment of bacterial peritonitis in patients with gastrointestinal cancer: an observational multicenter study.

Alix Riescher-Tuczkiewicz, Jules Grégory, Frederic Bert, Magaly Zappa, Anna Pellat, Valerie Lalande, Claire Gallois, Jean-Luc Mainardi, Jean-Baptiste Bachet, Jérôme Robert and 6 more

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Article in Therapeutic advances in medical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alix Riescher-TuczkiewiczPancreatology and Digestive Oncology Department, Beaujon Hospital, AP-HP, Paris-Cité University, 100 Boulevard du Général Leclerc, Clichy 92110, France.ORCID https://orcid.org/0000-0002-7489-9931
Jules GrégoryInserm, INRAE, Center for Research in Epidemiology and Statistics, France and Radiology Department, Hôpital Beaujon, AP-HP.
Frederic BertBacteriology Department, Beaujon Hospital, AP-HP, Paris-Cité University, Clichy, France.
Magaly ZappaService d'Imagerie Médicale, Centre Hospitalier de Cayenne, Cayenne, France.
Anna PellatOncology Department, Saint Antoine Hospital, AP-HP, Paris, France.
Valerie LalandeBacteriology Department, Saint Antoine Hospital, AP-HP, Paris, France.
Claire GalloisDigestive Oncology Department, Européen Georges Pompidou Hospital, AP-HP, Paris, France.
Jean-Luc MainardiBacteriology Department, Européen Georges Pompidou Hospital, AP-HP, Paris, France.
Jean-Baptiste BachetHepato-Gastroenterology Department, Pitié Salpêtrière Hospital, AP-HP, Paris, France.
Jérôme RobertLaboratoire de Bactériologie-Hygiène, DMU BioGeM, AP-HP, Sorbonne Université, Site Pitié-Salpêtrière, Paris, France.
Anne Sophie BourrelBacteriology Department, Cochin Hospital, AP-HP, Paris, France.
Romain CoriatHepato-Gastroenterology Department, Cochin Hospital, AP-HP, Paris, France.
Dominique ThabutHepato-Gastroenterology Department, Pitié Salpêtrière Hospital, AP-HP, Paris, France.
Pascal HammelDigestive and Medical Oncology Department, Paul Brousse Hospital, AP-HP, Paris-Saclay University, Villejuif, France.ORCID https://orcid.org/0000-0002-4630-4996
Vinciane ReboursHepato-Gastroenterology Department, Pitié Salpêtrière Hospital, AP-HP, Paris, France.
Diane LorenzoPancreatology and Digestive Oncology Department, Beaujon Hospital, AP-HP, Paris-Cité University, Clichy, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bacterial peritonitis (BP) in patients with gastrointestinal (GI) cancer has been poorly described, and its prevalence is unknown. Objectives: This study aimed to evaluate in patients with both GI cancer and ascites the prevalence of BP, associated features, mechanisms, prognosis, and the diagnostic performance of neutrophil count in ascites. Design: A retrospective, multicenter, observational study. Methods: All patients with GI cancer and ascites who underwent at least one paracentesis sample analyzed for bacteriology over a 1-year period were included. BP was defined by a positive ascites culture combined with clinical and/or biological signs compatible with infection. Secondary BP was defined as BP related to a direct intra-abdominal infectious source. Results: Five hundred fifty-seven ascites from 208 patients included were analyzed. Twenty-eight patients had at least one episode of BP and the annual prevalence rate of BP was 14%. Among the 28 patients with BP, 19 (65%) patients had proven secondary BP and 17 (59%) patients had multi-microbial BP, mainly due to Conclusion: BP is not rare in patients with GI cancer and is associated with a poor short-term prognosis. When a patient with GI cancer is diagnosed with BP, a secondary cause should be sought. Further studies are needed to better define the best management of these patients.

Indexed as

ascitesdiagnosisEnterobacteralesinfectionmalignant ascitessecondary bacterial peritonitis

Identifiers

PMID38845791
PMCPMC11155326

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.