Evidence map›Paper›PMID 38844771›Full record

ArticleScientific reports2024

Factors associated with the use of benzodiazepine and opioid prescription drug in the student population: a cross-sectional study.

Charlotte Thomas, Thibaut Dondaine, Clément Caron, Axel Bastien, Nathalie Chérot, Sylvie Deheul, Sophie Gautier, Olivier Cottencin, Sophie Moreau-Crépeaux, Régis Bordet and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Charlotte ThomasDepartment of Psychiatry and Addiction Medicine, CHU Lille, Lille, France. charlotte_thomas@orange.fr.
Thibaut DondaineUniversity of Lille, Inserm, CHU Lille, Lille Neuroscience and Cognition, Degenerative and Vascular Cognitive Disorders, UMR-S1172, Lille, France.
Clément CaronDepartment of Psychiatry and Addiction Medicine, CHU Lille, Lille, France.
Axel BastienDepartment of Psychiatry and Addiction Medicine, CHU Lille, Lille, France.
Nathalie ChérotIMPECS - IMPact de l'Environnement Chimique sur la Santé humaine, Department of Occupational Health, University of Lille, CHU Lille, Institut Pasteur de Lille, ULR 4483, 59000, Lille, France.
Sylvie DeheulCHU Lille, Pharmacology Department, Pharmacovigilance and Addictovigilance center, Lille, France.
Sophie GautierUniversity of Lille, Inserm, CHU Lille, Lille Neuroscience and Cognition, Degenerative and Vascular Cognitive Disorders, UMR-S1172, Lille, France.
Olivier CottencinLille Neuroscience & Cognition Centre (LiNC), Department of Psychiatry and Addiction Medicine, University of Lille, CHU Lille, INSERM U-1172, Plasticity & SubjectivitY (PSY) team, Lille, France.
Sophie Moreau-CrépeauxUniversity of Lille, University student health services, Lille, France.
Régis BordetUniversity of Lille, Inserm, CHU Lille, Lille Neuroscience and Cognition, Degenerative and Vascular Cognitive Disorders, UMR-S1172, Lille, France.
Louise CartonUniversity of Lille, Inserm, CHU Lille, Lille Neuroscience and Cognition, Degenerative and Vascular Cognitive Disorders, UMR-S1172, Lille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The misuse of benzodiazepines and opioid medications is frequent in students. To improve our understanding of this behavior, we aimed to identify factors associated with separate and concomitant use of these substances. Anonymous self-reported questionnaires were e-mailed to students enrolled at a French university between March and July 2021, covering: sociodemographic characteristics, academics, psychoactive substance use, ADHD symptomatology (adulthood and childhood), and psychiatric/psychological or addiction follow-up. Factors associated with the use of benzodiazepines and opioid medications included female sex (OR = 1.41 [1.08; 1.86]) and OR = 1.38 [1.06; 1.79], respectively), older age (OR = 1.65 [1.04; 2.6] and OR = 2.17 [1.4; 3.36], respectively), current psychiatric/psychological follow-up (OR = 6.53 [5.18; 8.24] and OR= 1.5 [1.12; 2.0], respectively), ADHD symptomatology (OR= 2.33 [1.71;3.16] and OR= 1.61 [1.15; 2.24], respectively), polyconsumption (tobacco use for benzodiazepine users, OR = 1.38 [1.04; 1.82]; alcohol use OR = 1.67 [1.17; 2.39] and tobacco use OR = 1.62 [1.23; 2.14] for opioid users). These factors were even more strongly associated with the concomitant use of benzodiazepines and opioid medications: older age (OR = 3.64 [2.22; 5.99]), female sex (OR = 1.54 [1.1; 2.14]), grade repetition (OR = 1.7 [1.14; 2.54]), psychiatric/psychological follow-up (OR = 4.51 [3.35;6.06]), ADHD symptomatology (OR = 5.3 [3.69; 7.63]), polyconsumption (tobacco use OR = 2.05 [1.39; 3] and cannabis use, OR = 2.07 [1.97; 4.16]. The factors associated with the use of benzodiazepines and prescription opioids identified in this study could lead to the development of targeted prevention methods.

Indexed as

Analgesics, OpioidBenzodiazepinesStudentsAdolescentAdultAttention Deficit Disorder with HyperactivityCross-Sectional StudiesFemaleFranceHumansMalePrescription Drug MisusePrescription DrugsSubstance-Related DisordersSurveys and QuestionnairesYoung AdultAnalgesics, OpioidBenzodiazepinesPrescription Drugs

Identifiers

PMID38844771
PMCPMC11156936

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.