Evidence map›Paper›PMID 38844741›Full record

ArticleMolecular diversity2025

Synthesis and characterization of novel bis(thiosemicarbazone) complexes and investigation of their acetylcholinesterase and glutathione S-transferase activities with in silico and in vitro studies.

Melike Donmez, Memet Sekerci, Ragip Adiguzel, Ercan Oğuz, Fikret Türkan, Umit Yildiko, Naki Colak

Abstract read
In one paragraph

Article in Molecular diversity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Melike DonmezAnkara Customs Accounting Directorate, 06590, Ankara, Turkey.ORCID http://orcid.org/0000-0002-0830-8056
Memet SekerciDepartment of Chemistry, Faculty of Science, Firat University, 23119, Elazıg, Turkey.ORCID http://orcid.org/0000-0002-7730-645X
Ragip AdiguzelDepartment of Chemistry and Chemical Process Technologies, Vocational School of Tunceli, Munzur University, 62000, Tunceli, Turkey. radiguzel@munzur.edu.tr.ORCID http://orcid.org/0000-0002-7050-0575
Ercan OğuzDepartment of Medical Services and Techniques, Health Services Vocational School, Igdır University, 76000, Igdır, Turkey.ORCID http://orcid.org/0000-0002-8737-9986
Fikret TürkanDepartment of Basic Sciences, Faculty of Dentistry, Igdır University, 76000, Igdır, Turkey.ORCID http://orcid.org/0000-0002-0538-3157
Umit YildikoDepartment of Bioengineering, Architecture and Engineering Faculty, Kafkas University, 36100, Kars, Turkey.ORCID http://orcid.org/0000-0001-8627-9038
Naki ColakDepartment of Chemistry, Faculty of Arts and Sciences, Hitit University, 19100, Corum, Turkey.ORCID http://orcid.org/0000-0001-7181-9556

Funding

Firat University Scientific Research Projects Unit (FUBAP) FF.1938
6 · The paper itself

Abstract

In this study, firstly, bis(thiosemicarbazone) ligand [L: 2,2'-(2-(2-(4-methoxyphenyl)hydrazineylidene)cyclohexane-1,3-diylidene)bis(hydrazine-1-carbothioamide)] was synthesized by the condensation reaction of thiosemicarbazide and ketone compound (2-(2-(4-methoxyphenyl)hydrazone)cyclohexane-1,3-dione). The metal complexes were synthesized by the reaction of obtained ligand (L) with CuCl

Indexed as

AcetylcholinesteraseCholinesterase InhibitorsCoordination ComplexesGlutathione TransferaseThiosemicarbazonesHumansLigandsMolecular Docking SimulationAcetylcholinesteraseCholinesterase InhibitorsCoordination ComplexesGlutathione TransferaseLigandsThiosemicarbazonesBis(thiosemicarbazone) ligandsEnzyme inhibitionMetal complexesMolecular docking

Identifiers

PMID38844741
PMCPMC11909086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.