Evidence map›Paper›PMID 38844697›Full record

ArticleNeuroradiology2024

Stenting with dual-layer CGuard stent in acute sub-occlusive carotid artery stenosis and in tandem occlusions: a monocentric study.

Mousa Zidan, Christian Gronemann, Nils Christian Lehnen, Felix Bode, Johannes Weller, Gabor Petzold, Alexander Radbruch, Daniel Paech, Franziska Dorn

Abstract read
In one paragraph

Article in Neuroradiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mousa Zidan *Department of Neuroradiology, Bonn University Hospital, Venusberg-Campus1, Gebäude 81, 53127, Bonn, Germany. mousa.zidan@ukbonn.de.ORCID http://orcid.org/0000-0002-5236-3992
Christian Gronemann *Department of Neuroradiology, Bonn University Hospital, Venusberg-Campus1, Gebäude 81, 53127, Bonn, Germany.
Nils Christian LehnenDepartment of Neuroradiology, Bonn University Hospital, Venusberg-Campus1, Gebäude 81, 53127, Bonn, Germany.
Felix BodeDepartment of Neurology, Bonn University Hospital, Bonn, Germany.
Johannes WellerDepartment of Neurology, Bonn University Hospital, Bonn, Germany.
Gabor PetzoldDepartment of Neurology, Bonn University Hospital, Bonn, Germany.
Alexander RadbruchDepartment of Neuroradiology, Bonn University Hospital, Venusberg-Campus1, Gebäude 81, 53127, Bonn, Germany.
Daniel Paech *Department of Neuroradiology, Bonn University Hospital, Venusberg-Campus1, Gebäude 81, 53127, Bonn, Germany.
Franziska Dorn *Department of Neuroradiology, Bonn University Hospital, Venusberg-Campus1, Gebäude 81, 53127, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDouble-layer design carotid stents have been cast in a negative light since several investigations reported high rates of in-stent occlusions, at least in the acute setting of tandem occlusions. CGuard is a new generation double-layered stent that was designed to prevent periinterventional embolic events. The aim of this study was to analyze the safety and efficacy of the CGuard in emergent CAS and for the acute treatment of tandem occlusions in comparison with the single-layer Carotid Wallstent (CWS) system.

methodsAll patients who underwent CAS with CGuard or CWS after intracranial mechanical thrombectomy (MT) between 11/2018 and 12/2022 were identified from our local thrombectomy registry. Clinical, interventional and neuroimaging data were analyzed. Patency of the stent was assessed within 72 h. Intracranial hemorrhage and modified Rankin score (mRS) at discharge were the main endpoints.

resultsIn total, 86 stent procedures in 86 patients were included (CWS: 44, CGuard: 42). CGuard had a lower, but not statistically significant rate (p = 0.431) of in-stent occlusions (n = 2, 4.8%) when compared to the CWS (n = 4, 9.1%). Significant in-stent stenosis was found in one case in each group. There was no statistically significant difference in functional outcome at discharge between the two groups with a median mRS for CGuard of 2 (IQR:1-5) vs. CWS 3 (IQR:2-4).

conclusionIn our series, the rate of in-stent occlusions after emergent CAS was lower with the dual-layer CGuard when compared to the monolayer CWS. Further data are needed to evaluate the potential benefit of the design in more detail.

Indexed as

Carotid StenosisStentsAgedAged, 80 and overFemaleHumansMaleMiddle AgedProsthesis DesignRetrospective StudiesThrombectomyCarotid artery stentingDual-layer stentIn-stent occlusionTandem occlusionThrombectomy

Identifiers

PMID38844697
PMCPMC11322317

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.