Evidence map›Paper›PMID 38844663›Full record

ReviewNature nanotechnology2024

Towards realizing nano-enabled precision delivery in plants.

Gregory V Lowry, Juan Pablo Giraldo, Nicole F Steinmetz, Astrid Avellan, Gozde S Demirer, Kurt D Ristroph, Gerald J Wang, Christine O Hendren, Christopher A Alabi, Adam Caparco and 12 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature nanotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
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  4. A GAPlant communications · 2026
    Article
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  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
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  16. Single-walled carbon nanotube-mediated plasmid DNA delivery in the model monocotTurkish journal of biology = Turk biyoloji dergisi · 2026
    Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Gregory V LowryCivil and Environmental Engineering, Carnegie Mellon University, Pittsburgh, PA, USA. glowry@andrew.cmu.edu.ORCID http://orcid.org/0000-0001-8599-008X
Juan Pablo GiraldoBotany and Plant Sciences, University of California, Riverside, Riverside, CA, USA. juanpablo.giraldo@ucr.edu.ORCID http://orcid.org/0000-0002-8400-8944
Nicole F SteinmetzDepartment of NanoEngineering, University of California San Diego, San Diego, CA, USA.
Astrid AvellanUMR 5563 CNRS, Toulouse, Occitanie, France.ORCID http://orcid.org/0000-0001-6081-4389
Gozde S DemirerChemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.ORCID http://orcid.org/0000-0002-3007-1489
Kurt D RistrophAgricultural and Biological Engineering, Purdue University, West Lafayette, IN, USA.ORCID http://orcid.org/0000-0002-6771-6105
Gerald J WangCivil and Environmental Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-0631-011X
Christine O HendrenGeological and Environmental Sciences, Appalachian State University, Boone, NC, USA.
Christopher A AlabiChemical and Biomolecular Engineering, Cornell University, Ithaca, NY, USA.ORCID http://orcid.org/0000-0003-2654-018X
Adam CaparcoDepartment of NanoEngineering, University of California San Diego, San Diego, CA, USA.
Washington da SilvaThe Connecticut Agricultural Research Station, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-5558-286X
Ivonne González-GamboaDepartment of Molecular Biology, University of California San Diego, San Diego, CA, USA.ORCID http://orcid.org/0000-0003-1617-8252
Khara D GriegerApplied Ecology, North Carolina State University, Raleigh, NC, USA.ORCID http://orcid.org/0000-0002-0821-0534
Su-Ji JeonBotany and Plant Sciences, University of California, Riverside, Riverside, CA, USA.ORCID http://orcid.org/0000-0002-5917-8837
Mariya V KhodakovskayaApplied Science, University of Arkansas, Little Rock, AK, USA.ORCID http://orcid.org/0000-0001-6398-4105
Hagay KohayCivil and Environmental Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Vivek KumarCivil and Environmental Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0003-4737-3288
Raja MuthuramalingamThe Connecticut Agricultural Research Station, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-7471-918X
Hanna PoffenbargerPlant and Soil Sciences, University of Kentucky, Lexington, KY, USA.ORCID http://orcid.org/0000-0002-7715-373X
Swadeshmukul SantraDepartment of Chemistry and Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, USA.ORCID http://orcid.org/0000-0001-5929-5323
Robert D TiltonChemical Engineering and Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Jason C WhiteThe Connecticut Agricultural Research Station, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-5001-8143

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 101041729National Science Foundation (NSF) 2133568National Science Foundation (NSF) 2134535National Science Foundation (NSF) 2222373United States Department of Agriculture | Agricultural Research Service (USDA Agricultural Research Service) 2022-67021-38078
6 · The paper itself

Abstract

Nanocarriers (NCs) that can precisely deliver active agents, nutrients and genetic materials into plants will make crop agriculture more resilient to climate change and sustainable. As a research field, nano-agriculture is still developing, with significant scientific and societal barriers to overcome. In this Review, we argue that lessons can be learned from mammalian nanomedicine. In particular, it may be possible to enhance efficiency and efficacy by improving our understanding of how NC properties affect their interactions with plant surfaces and biomolecules, and their ability to carry and deliver cargo to specific locations. New tools are required to rapidly assess NC-plant interactions and to explore and verify the range of viable targeting approaches in plants. Elucidating these interactions can lead to the creation of computer-generated in silico models (digital twins) to predict the impact of different NC and plant properties, biological responses, and environmental conditions on the efficiency and efficacy of nanotechnology approaches. Finally, we highlight the need for nano-agriculture researchers and social scientists to converge in order to develop sustainable, safe and socially acceptable NCs.

Indexed as

NanotechnologyPlantsAgricultureDrug Delivery SystemsNanoparticles

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.