ArticleNature communications2024
Development and organization of the retinal orientation selectivity map.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Domain-like patterning of dendritic asymmetry and orientation defined by gap junctions in the mouse retina.iScience · 2025Article
- Differential topographic organization and retinal inheritance of direction and orientation selectivity in the visual thalamus.Nature communications · 2025Article
- Sound feature representations decorrelate across the mouse auditory pathway.PLoS biology · 2025Article
- Do the receptive fields in the primary visual cortex span a variability over the degree of elongation of the receptive fields?Journal of computational neuroscience · 2025Article
- Experience influences the refinement of feature selectivity in the mouse primary visual thalamus.Neuron · 2025Article
- Orientation selectivity properties for the affine Gaussian derivative and the affine Gabor models for visual receptive fields.Journal of computational neuroscience · 2025Article
- Compartmentalized pooling generates orientation selectivity in wide-field amacrine cells.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- More Than a Small Brain: The Importance of Studying Neural Function during Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
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Abstract
Orientation or axial selectivity, the property of neurons in the visual system to respond preferentially to certain angles of visual stimuli, plays a pivotal role in our understanding of visual perception and information processing. This computation is performed as early as the retina, and although much work has established the cellular mechanisms of retinal orientation selectivity, how this computation is organized across the retina is unknown. Using a large dataset collected across the mouse retina, we demonstrate functional organization rules of retinal orientation selectivity. First, we identify three major functional classes of retinal cells that are orientation selective and match previous descriptions. Second, we show that one orientation is predominantly represented in the retina and that this predominant orientation changes as a function of retinal location. Third, we demonstrate that neural activity plays little role on the organization of retinal orientation selectivity. Lastly, we use in silico modeling followed by validation experiments to demonstrate that the overrepresented orientation aligns along concentric axes. These results demonstrate that, similar to direction selectivity, orientation selectivity is organized in a functional map as early as the retina.
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