Evidence map›Paper›PMID 38844366›Full record

ReviewAJNR. American journal of neuroradiology2025

Meningioma: Molecular Updates from the 2021 World Health Organization Classification of CNS Tumors and Imaging Correlates.

Neetu Soni, Manish Ora, Girish Bathla, Denes Szekeres, Amit Desai, Jay J Pillai, Amit Agarwal

Abstract readReview
In one paragraph

Review in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Molecular Brain Tumor Imaging Beyond [AJR. American journal of roentgenology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Neetu SoniFrom the Department of Radiology (N.S., J.J.P., A.D., A.A.), Mayo Clinic, Jacksonville, Florida Soni.Neetu@mayo.edu.ORCID 0000-0003-2082-1634
Manish OraDepartment of Nuclear Medicine (M.O.), Sanjay Gandhi Post-Graduate Institute of Medical Sciences, Lucknow, India.ORCID 0000-0002-9748-2215
Girish BathlaDepartment of Radiology (G.B., J.P.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0003-3170-242X
Denes SzekeresUniversity of Rochester School of Medicine and Dentistry (D.S.), Rochester, New York.
Amit DesaiFrom the Department of Radiology (N.S., J.J.P., A.D., A.A.), Mayo Clinic, Jacksonville, Florida.ORCID 0000-0002-3073-6823
Jay J PillaiDepartment of Radiology (G.B., J.P.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-8306-7192
Amit AgarwalFrom the Department of Radiology (N.S., J.J.P., A.D., A.A.), Mayo Clinic, Jacksonville, Florida.ORCID 0000-0001-9139-8007

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meningiomas, the most common primary intracranial neoplasms, account for more than one-third of primary CNS tumors. While traditionally viewed as benign, meningiomas can be associated with considerable morbidity, and specific meningioma subgroups display more aggressive behavior with higher recurrence rates. The risk stratification for recurrence has been primarily associated with the World Health Organization (WHO) histopathologic grade and extent of resection. However, a growing body of literature has highlighted the value of molecular characteristics in assessing recurrence risk. While maintaining the previous classification system, the 5th edition of the 2021 WHO Classification of Central Nervous System tumors (CNS5) book expands upon the molecular information in meningiomas to help guide management. The WHO CNS5 stratifies meningioma into 3 grades (1-3) based on histopathology criteria and molecular profile. The telomerase reverse transcriptase promoter mutations and cyclin-dependent kinase inhibitor 2A/B (

Indexed as

Meningeal NeoplasmsMeningiomaHumansWorld Health Organization

Identifiers

PMID38844366
PMCPMC11878982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.