Evidence map›Paper›PMID 38844362›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2024

In Vivo PET Imaging of

Truc T Pham, Alicia Chenoweth, Natasha Patel, Arshiya Banu, Gabriel Osborn, Philip J Blower, Sophia N Karagiannis, Michelle T Ma

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Tracking macrophages by direct and indirectEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. In vivo tracking of ex-vivo-generatedMolecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Truc T PhamDepartment of Imaging Chemistry and Biology, School of Bioengineering and Imaging Sciences, King's College London, London, United Kingdom; truc.pham@kcl.ac.uk sophia.karagiannis@kcl.ac.uk michelle.ma@kcl.ac.uk.
Alicia ChenowethSt. John's Institute of Dermatology, School of Basic and Medical Biosciences, King's College London, London, United Kingdom; and.
Natasha PatelDepartment of Imaging Chemistry and Biology, School of Bioengineering and Imaging Sciences, King's College London, London, United Kingdom.
Arshiya BanuDepartment of Imaging Chemistry and Biology, School of Bioengineering and Imaging Sciences, King's College London, London, United Kingdom.
Gabriel OsbornSt. John's Institute of Dermatology, School of Basic and Medical Biosciences, King's College London, London, United Kingdom; and.
Philip J BlowerDepartment of Imaging Chemistry and Biology, School of Bioengineering and Imaging Sciences, King's College London, London, United Kingdom.
Sophia N KaragiannisSt. John's Institute of Dermatology, School of Basic and Medical Biosciences, King's College London, London, United Kingdom; and truc.pham@kcl.ac.uk sophia.karagiannis@kcl.ac.uk michelle.ma@kcl.ac.uk.
Michelle T MaDepartment of Imaging Chemistry and Biology, School of Bioengineering and Imaging Sciences, King's College London, London, United Kingdom; truc.pham@kcl.ac.uk sophia.karagiannis@kcl.ac.uk michelle.ma@kcl.ac.uk.

Funding

Breast Cancer Now 147Breast Cancer Now KCL-BCN-Q3Cancer Research UK C30122/A11527Cancer Research UK C30122/A15774Cancer Research UK C4278/A27066Cancer Research UK C63178/A24959Medical Research Council MR/L023091/1Medical Research Council MR/N013700/1Wellcome Trust WT088641/Z/09/ZWellcome Trust WT201959/Z/16/ZWellcome Trust WT212885/Z/18/Z
6 · The paper itself

Abstract

Natural killer (NK) cells can kill cancer cells via antibody-dependent cell-mediated cytotoxicity (ADCC): a tumor-associated IgG antibody binds to the Fcγ receptor CD16 on NK cells via the antibody Fc region and activates the cytotoxic functions of the NK cell. Here, we used PET imaging to assess NK cell migration to human epidermal growth factor receptor 2 (HER2)-positive HCC1954 breast tumors, examining the influence of HER2-targeted trastuzumab antibody treatment on NK cell tumor accumulation.

Indexed as

Killer Cells, NaturalRadioisotopesTrastuzumabZirconiumAnimalsBreast NeoplasmsCell Line, TumorCell MovementErb-b2 Receptor Tyrosine KinasesFemaleHumansIsotope LabelingMicePositron-Emission TomographyPositron Emission Tomography Computed TomographyErb-b2 Receptor Tyrosine KinasesRadioisotopesTrastuzumabZirconiumZirconium-89ADCCcell trackingHER2 receptornatural killer celltrastuzumab

Identifiers

PMID38844362
PMCPMC11218727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.