Evidence map›Paper›PMID 38843334›Full record

ArticleScience (New York, N.Y.)2024

Axis formation in annual killifish: Nodal and β-catenin regulate morphogenesis without Huluwa prepatterning.

Philip B Abitua, Laura M Stump, Deniz C Aksel, Alexander F Schier

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Life-long behavioral screen reveals an architecture of vertebrate aging.bioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Philip B AbituaGenome Sciences, University of Washington, Seattle, WA 98105, USA.ORCID 0000-0002-8264-0807
Laura M Stump *Genome Sciences, University of Washington, Seattle, WA 98105, USA.ORCID 0009-0004-5325-8803
Deniz C Aksel *Biophysics Program, Harvard University, Cambridge, MA 02138, USA.
Alexander F SchierDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0001-7645-5325

Funding

MOLECULAR BIOPHYSICS TRAINING GRANTT32GM008313 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MURTHY, VENKATESH N · 1989 to 2023
$14.6M
Genetic Mechanisms of Axis Formation in VertebratesR37GM056211 · NIGMS · HARVARD UNIVERSITY · PI SCHIER, ALEXANDER F · 2016 to 2019
$1.5M
NIGMS NIH HHS R37 GM056211NIGMS NIH HHS T32 GM008313
6 · The paper itself

Abstract

Axis formation in fish and amphibians typically begins with a prepattern of maternal gene products. Annual killifish embryogenesis, however, challenges prepatterning models as blastomeres disperse and then aggregate to form the germ layers and body axes. We show that

Indexed as

beta CateninFundulidaeMorphogenesisNodal ProteinAnimalsBlastulaBody PatterningCell MovementCell NucleusGerm LayersKillifishesSignal Transductionbeta CateninNodal Protein

Identifiers

PMID38843334
PMCPMC12338973

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.