Evidence map›Paper›PMID 38842722›Full record

ArticlePediatric nephrology (Berlin, Germany)2024

Allopurinol use leading to xanthine nephrolithiasis in pediatric tumor lysis syndrome: a case series.

Shrea Goswami, Amy E Hanson, Evan Rajadhyaksha, Pankaj P Dangle, Andrew L Schwaderer

Abstract readCase Reports
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In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Tumour lysis syndrome.Nature reviews. Disease primers · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shrea Goswami *Indiana University Department of Pediatrics, Division of Nephrology, Riley Children's Hospital, 705 Riley Drive, Indianapolis, IN, 46202, USA.
Amy E Hanson *Indiana University Department of Pediatrics, Division of Critical Care, Indianapolis, IN, USA.
Evan RajadhyakshaIndiana University Department of Pediatrics, Division of Nephrology, Riley Children's Hospital, 705 Riley Drive, Indianapolis, IN, 46202, USA.
Pankaj P DangleIndiana University Department of Urology, Division of Pediatric Urology, Indianapolis, IN, USA.
Andrew L SchwadererIndiana University Department of Pediatrics, Division of Nephrology, Riley Children's Hospital, 705 Riley Drive, Indianapolis, IN, 46202, USA. schwadea@iu.edu.ORCID 0000-0003-0560-4666

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor lysis syndrome (TLS) is a life-threatening metabolic disorder caused by massive tumor lysis. Allopurinol, a xanthine oxidase inhibitor, is initiated during chemotherapy to prevent hyperuricemia and subsequent acute kidney injury (AKI). We report two cases of xanthine nephrolithiasis during TLS in newly diagnosed hematologic malignancy patients receiving prophylactic allopurinol. Allopurinol use likely promoted xanthine crystallization, stone formation, and AKI.

Indexed as

AllopurinolTumor Lysis SyndromeAcute Kidney InjuryAdolescentChildEnzyme InhibitorsFemaleHumansHyperuricemiaMaleNephrolithiasisXanthineAllopurinolEnzyme InhibitorsXanthineAcute kidney injuryNephrolithiasisPediatricsTumor lysis syndromeXanthine oxidase inhibitors

Identifiers

PMID38842722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.