Evidence map›Paper›PMID 38842644›Full record

ArticleSleep & breathing = Schlaf & Atmung2024

Management of sleep-disordered breathing in patients with syndromic hemifacial macrosomia.

Barbara Madini, Sonia Khirani, Meryl Vedrenne-Cloquet, Eva Galliani, Catherine Tomat, Charlotte Célérier, Maria Francesca Patria, Lucie Griffon, Natacha Kadlub, Vincent Couloigner and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Barbara MadiniPediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker Enfants Malades, 149 Rue de Sèvres, 75015, Paris, France.
Sonia KhiraniPediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker Enfants Malades, 149 Rue de Sèvres, 75015, Paris, France.
Meryl Vedrenne-CloquetPediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker Enfants Malades, 149 Rue de Sèvres, 75015, Paris, France.
Eva GallianiPediatric Maxillofacial and Plastic Surgery Department, AP-HP, Hôpital Necker Enfants Malades, Paris, France.
Catherine TomatPediatric Maxillofacial and Plastic Surgery Department, AP-HP, Hôpital Necker Enfants Malades, Paris, France.
Charlotte CélérierDepartment of Pediatric Otolaryngology-Head and Neck Surgery, AP-HP, Hôpital Necker Enfants Malades, Paris, France.
Maria Francesca PatriaFondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, SC Pediatria Pneumo-Infettivologia, Milan, Italy.
Lucie GriffonPediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker Enfants Malades, 149 Rue de Sèvres, 75015, Paris, France.
Natacha KadlubPediatric Maxillofacial and Plastic Surgery Department, AP-HP, Hôpital Necker Enfants Malades, Paris, France.
Vincent CouloignerDepartment of Pediatric Otolaryngology-Head and Neck Surgery, AP-HP, Hôpital Necker Enfants Malades, Paris, France.
Arnaud PicardPediatric Maxillofacial and Plastic Surgery Department, AP-HP, Hôpital Necker Enfants Malades, Paris, France.
Françoise DenoyelleDepartment of Pediatric Otolaryngology-Head and Neck Surgery, AP-HP, Hôpital Necker Enfants Malades, Paris, France.
Brigitte FaurouxPediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker Enfants Malades, 149 Rue de Sèvres, 75015, Paris, France. brigitte.fauroux@aphp.fr.ORCID 0000-0001-6092-2662

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients with syndromic hemifacial microsomia (SHFM) are at risk of obstructive sleep apnea (OSA). The aim of the study was to describe the prevalence of OSA and its management, especially in patients with Goldenhar syndrome (GS).

methodsThe respiratory polygraphies and clinical management of 15 patients, aged 2 to 23 years, evaluated at a national reference center, were analyzed.

resultsFour (27%) patients had no OSA, 4 (27%) had mild OSA, and 7 (46%), of whom 5 were ≤ 2 years old, had severe OSA. None of the patients had central apneas. Only one patient had alveolar hypoventilation, and another one had nocturnal hypoxemia. Two patients had severe OSA despite prior adenoidectomy or mandibular distraction osteogenesis. Median duration of follow-up was 3.5 years (range 0.5-9 years). None of the patients without OSA or with mild OSA at baseline respiratory polygraphy developed OSA during the follow up. Among the 7 patients with severe OSA, 3 required continuous positive airway pressure or noninvasive ventilation, and one patient required a tracheostomy.

conclusionIn conclusion, patients with SHFM are at high risk of severe OSA at any age, underlining the importance of systematic sleep studies to diagnose and evaluate the severity of OSA. Individualized treatment should be privileged, based on a careful examination of the entire upper airway, taking in account potential associated risk factors. All patients with SHFM should be managed by a pediatric expert multidisciplinary medical/surgical team until the end of post pubertal growth.

Indexed as

Goldenhar SyndromeSleep Apnea, ObstructiveAdolescentChildChild, PreschoolContinuous Positive Airway PressureCross-Sectional StudiesFemaleFollow-Up StudiesHumansMalePolysomnographyYoung AdultContinuous positive airway pressureNoninvasive ventilationObstructive sleep apneaSleep-disordered breathingSyndromic hemifacial microsomiaUpper airway surgery

Identifiers

PMID38842644

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.