Evidence map›Paper›PMID 38842578›Full record

ReviewJournal of cell science2024

Histone acylation at a glance.

Saikat Bhattacharya, Benjamin P Tu

Abstract readReview
In one paragraph

Review in Journal of cell science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Saikat BhattacharyaDepartment of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75390-9038, USA.
Benjamin P TuDepartment of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75390-9038, USA.ORCID 0000-0001-5545-9183

Funding

UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI JAY D. HORTON · 2022 to 2026
$7.4M
Control of Stem Cell Dynamics by a Niche at Steady-State and During AgingR35GM136270 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DINARDO, STEPHEN FRANCIS · 2020 to 2024
$2.1M
Redox regulation of protein functions linked to neurodegenerationR01NS115546 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI TU, BENJAMIN P · 2019 to 2023
$2.0M
Howard Hughes Medical InstituteNIDDK NIH HHS P30 DK127984NIGMS NIH HHS R35 GM136270NIH HHS R35GM136270NINDS NIH HHS R01 NS115546
6 · The paper itself

Abstract

An important mechanism of gene expression regulation is the epigenetic modification of histones. The cofactors and substrates for these modifications are often intermediary metabolites, and it is becoming increasingly clear that the metabolic and nutritional state of cells can influence these marks. These connections between the balance of metabolites, histone modifications and downstream transcriptional changes comprise a metabolic signaling program that can enable cells to adapt to changes in nutrient availability. Beyond acetylation, there is evidence now that histones can be modified by other acyl groups. In this Cell Science at a Glance article and the accompanying poster, we focus on these histone acylation modifications and provide an overview of the players that govern these acylations and their connections with metabolism.

Indexed as

HistonesProtein Processing, Post-TranslationalAcylationAnimalsEpigenesis, GeneticHumansHistonesAcetylationAcylationChromatinEpigeneticsHistone modificationMetabolism

Identifiers

PMID38842578
PMCPMC11213524

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.