ArticleThe Plant cell2024
Phosphorylated transcription factor PuHB40 mediates ROS-dependent anthocyanin biosynthesis in pear exposed to high light.
Article in The Plant cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- From genome to gene module: decoding the BsAlfin2-BsTT2 regulatory network controlling low temperature-induced anthocyanin biosynthesis inHorticulture research · 2026Article
- Multifaceted mechanisms underlying species- and cultivar-associated differential anthocyanin accumulation in fruits.Horticulture research · 2026Article
- Light-responsive PyNAC90 orchestrates anthocyanin biosynthesis through combinatorial transcriptional activation and COP1-mediated degradation in pear.Molecular horticulture · 2026Article
- Light Regulation of Anthocyanin Biosynthesis in Plants: From Mechanisms to Applications.Plant, cell & environment · 2026Review
- Advances in Physiological and Molecular Mechanisms of Heat Stress in Apple and Pear.Plants (Basel, Switzerland) · 2026Review
- Anthocyanin biosynthesis in blueberry is regulated by light and abscisic acid signaling via a VcABF2-miR156-VcSPL9 feedback loop.The New phytologist · 2026Article
- Anthocyanin accumulation in fruit crops: a multi-layered regulatory network integrating molecular, epigenetic, hormonal and environmental regulation.Molecular biology reports · 2026Review
- Transcription factor MdMYB6L represses anthocyanin biosynthesis of apple skin at low-altitude regions.Plant cell reports · 2026Article
- Quantitative phosphoproteomics profiling reveals the regulatory mechanisms underlying high light stress in maize and rice.Photosynthesis research · 2026Article
- Anthocyanin-Driven Dark Phenotypes in Stress Adaptation.Plants (Basel, Switzerland) · 2026Review
- Article
- Agrobacterium rhizogenes-mediated stable and transient transformation systems enable rapid functional validation of C6 aldehyde synthesis genes in peach.BMC plant biology · 2026Article
- The mitochondrial DnaJA protein LMA1 regulates reactive oxygen species homeostasis and anthocyanin biosynthesis inPlant diversity · 2026Article
- Molecular insights into the regulation of flavonoid biosynthesis in fruits.Horticulture research · 2026Article
- Identification of the BBX gene family and SmBBX5 positively regulate anthocyanin accumulation in eggplant (Solanum melongena L.).BMC genomics · 2025Article
- Genome-wide identification and functional analysis of U-box E3 ubiquitin ligases gene family related to drought stress response in Musa acuminata.BMC plant biology · 2025Article
- Hyperoside, a flavonoid, inducesScience advances · 2025Article
- Growth-Promoting Effects of Dark Septate Endophytes FungusJournal of fungi (Basel, Switzerland) · 2025Article
- The MdHB7L-MdICE1L-MdHOS1 Module Fine-Tunes Apple Cold Response via CBF-Dependent and CBF-Independent Pathways.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Splice it hot: How nuclear PP2A B'η regulates splicing fidelity by targeting the heat-stressed spliceosome.The Plant cell · 2025Article
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9 authors.
Funding
Abstract
Plants are increasingly vulnerable to environmental stresses because of global warming and climate change. Stress-induced reactive oxygen species (ROS) accumulation results in plant cell damage, even cell death. Anthocyanins are important antioxidants that scavenge ROS to maintain ROS homeostasis. However, the mechanism underlying ROS-induced anthocyanin accumulation is unclear. In this study, we determined that the HD-Zip I family member transcription factor PuHB40 mediates ROS-dependent anthocyanin biosynthesis under high-light stress in pear (Pyrus ussuriensis). Specifically, PuHB40 induces the PuMYB123-like-PubHLH3 transcription factor complex for anthocyanin biosynthesis. The PuHB40-mediated transcriptional activation depends on its phosphorylation level, which is regulated by protein phosphatase PP2A. Elevated ROS content maintains high PuHB40 phosphorylation levels while also enhancing the PuHB40-induced PuMYB123-like transcription by decreasing the PuPP2AA2 expression, ultimately leading to increased anthocyanin biosynthesis. Our study reveals a pathway regulating the ROS-induced anthocyanin biosynthesis in pears, further clarifying the mechanism underlying the abiotic stress-induced anthocyanin biosynthesis, which may have implications for improving plant stress tolerance.
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