Evidence map›Paper›PMID 38842147›Full record

ReviewNucleus (Austin, Tex.)2024

Not just binary: embracing the complexity of nuclear division dynamics.

Madison E Walsh, Grant A King, Elçin Ünal

Abstract readReview
In one paragraph

Review in Nucleus (Austin, Tex.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Madison E WalshDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA, USA.ORCID 0000-0002-1082-9678
Grant A KingDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA, USA.ORCID 0000-0001-9854-3174
Elçin ÜnalDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA, USA.ORCID 0000-0002-6768-609X

Funding

THE MOLECULAR BASIS OF CELL FUNCTIONT32GM007232 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID, UNAL, ELCIN · 1985 to 2022
$36.4M
Elucidating Cellular Aging and Quality Control Pathways through Meiotic DifferentiationR01AG071801 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI UNAL, ELCIN · 2021 to 2025
$1.9M
NIA NIH HHS R01 AG071801NIGMS NIH HHS T32 GM007232
6 · The paper itself

Abstract

Cell division presents a challenge for eukaryotic cells: how can chromosomes effectively segregate within the confines of a membranous nuclear compartment? Different organisms have evolved diverse solutions by modulating the degree of nuclear compartmentalization, ranging from complete nuclear envelope breakdown to complete maintenance of nuclear compartmentalization via nuclear envelope expansion. Many intermediate forms exist between these extremes, suggesting that nuclear dynamics during cell division are surprisingly plastic. In this review, we highlight the evolutionary diversity of nuclear divisions, focusing on two defining characteristics: (1) chromosome compartmentalization and (2) nucleocytoplasmic transport. Further, we highlight recent evidence that nuclear behavior during division can vary within different cellular contexts in the same organism. The variation observed within and between organisms underscores the dynamic evolution of nuclear divisions tailored to specific contexts and cellular requirements. In-depth investigation of diverse nuclear divisions will enhance our understanding of the nucleus, both in physiological and pathological states.

Indexed as

Cell Nucleus DivisionActive Transport, Cell NucleusAnimalsCell NucleusChromosomesHumansNuclear EnvelopeCell divisionmeiosismitosisnuclear compartmentalizationnuclear envelopenuclear pore complexnucleocytoplasmic transport

Identifiers

PMID38842147
PMCPMC11164224

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.