Observational studyFrontiers in public health2024
Clinical predictive value of the CRP-albumin-lymphocyte index for prognosis of critically ill patients with sepsis in intensive care unit: a retrospective single-center observational study.
Observational study in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prognostic value of the CALLY index in sepsis: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Prognostic value of the CALLY index for predicting in-hospital mortality in community-acquired pneumonia: Results from an elderly-predominant cohort.Irish journal of medical science · 2026Article
- Comparative Predictive Performance of Upper Gastrointestinal Bleeding Risk Scores and the CALLY Index in Geriatric Patients.Diagnostics (Basel, Switzerland) · 2026Article
- Association between energy adequacy and clinical outcomes in septic intensive care unit patients stratified by modified Nutrition Risk in the Critically Ill score.Journal of the Chinese Medical Association : JCMA · 2026Article
- Predictive Value of C-Reactive Protein-Albumin-Lymphocyte Index for Multiple Organ Failure Syndrome in Elderly Patients with Sepsis.Biochemical genetics · 2026Article
- Prognostic value of the lactate-based modified cally score in postoperative gastric cancer patients admitted to the ICU.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Prognostic Value of the C-Reactive Protein × Platelet-to-Lymphocyte Ratio for 28-Day Mortality in Patients With Sepsis: A Retrospective Cohort Study.Health science reports · 2026Article
- Association of Anemia Severity with Distinct Microbial and Inflammatory Signatures in Patients Receiving Vancomycin.Healthcare (Basel, Switzerland) · 2026Article
- Correlation between the CALLY index and postoperative stroke-associated pneumonia in patients with spontaneous intracerebral hemorrhage.Neurosurgical review · 2026Article
- Association between albumin-based nutritional inflammation indices and all-cause mortality in patients with severe pneumonia.BMC infectious diseases · 2026Article
- Lymphopenia in Bacterial Sepsis and SARS-CoV-2 Infection.Biomedicines · 2026Article
- The Role of the CALLY Index in 30-Day Mortality Prediction for Acute Mesenteric Ischemia: A Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2026Article
- Association between CALLY index and all-cause mortality in patients with rheumatoid arthritis.Frontiers in nutrition · 2026Article
- An exploratory study evaluating the predictive capacity of the CALLY index and SOFA-2 for 28-day all-cause mortality in patients with septic shock.Frontiers in medicine · 2026Article
- Baseline and dynamic CALLY index changes predict mortality in sepsis-associated acute kidney injury: a two-center retrospective cohort study.Frontiers in nutrition · 2026Article
- Achieving ≥70% of energy requirements during early enteral nutrition and short-term inflammatory-metabolic profiles in critically ill patients with sepsis: a prospective cohort study.Frontiers in nutrition · 2026Article
- External validation of the CALLY index and development of a laboratory-based model for 28-day mortality in sepsis: a two-center study.Frontiers in medicine · 2026Article
- Exploring the impact of the prognostic nutritional index and novel inflammatory markers on the prognosis of patients with hypostatic pneumonia.Annals of medicine and surgery (2012) · 2026Article
- Limited Utility of the CALLY Index in Enhancing Mortality Prediction for Trauma Patients in Intensive Care Units: A Retrospective Analysis.Risk management and healthcare policy · 2026Article
- Association between the C-reactive protein-albumin-lymphocyte index and cardiovascular incidence and mortality among patients with chronic kidney disease: a prospective study.Frontiers in immunology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Sepsis is a complex syndrome characterized by physiological, pathological, and biochemical abnormalities caused by infection. Its development is influenced by factors such as inflammation, nutrition, and immune status. Therefore, we combined C-reactive protein (CRP), albumin, and lymphocyte, which could reflect above status, to be the CRP-albumin-lymphocyte (CALLY) index, and investigated its association with clinical prognosis of critically ill patients with sepsis. Methods: This retrospective observational study enrolled critically ill patients with sepsis who had an initial CRP, albumin, and lymphocyte data on the first day of ICU admission. All data were obtained from the Affiliated Hospital of Jiangsu University. The patients were divided into quartiles (Q1-Q4) based on their CALLY index. The outcomes included 30-/60-day mortality and acute kidney injury (AKI) occurrence. The association between the CALLY index and these clinical outcomes in critically ill patients with sepsis was evaluated using Cox proportional hazards and logistic regression analysis. Results: A total of 1,123 patients (63.0% male) were included in the study. The 30-day and 60-day mortality rates were found to be 28.1 and 33.4%, respectively, while the incidence of AKI was 45.6%. Kaplan-Meier analysis revealed a significant association between higher CALLY index and lower risk of 30-day and 60-day mortality (log-rank Conclusion: The findings of this study indicated a significant association between the CALLY index and both 30-day and 60-day mortality, as well as the occurrence of AKI, in critically ill patients with sepsis. These findings suggested that the CALLY index may be a valuable tool in identifying sepsis patients who were at high risk for unfavorable outcomes.
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