ArticleFrontiers in public health2024
Depressive symptoms and all-cause mortality among middle-aged and older people in China and associations with chronic diseases.
Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of depression on mortality among older adult patients with hypertension: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Oral Structural and Functional Impairment in Relation to Depressive Outcomes in Older Adults: A Systematic Review and Meta-Analysis of Observational Studies.Diseases (Basel, Switzerland) · 2026Review
- Association Between Depressive Symptoms and Risk of New-Onset Chronic Liver Disease Among Middle-Aged and Elderly Chinese Adults: A Prospective Cohort Study Based on the China Health and Retirement Longitudinal Study.Healthcare (Basel, Switzerland) · 2026Article
- Gender Differences in the Protective Effects of Social Participation on Depressive Symptom Trajectories Among Middle-Aged and Older Adults in China: A Nationwide Longitudinal Study.Healthcare (Basel, Switzerland) · 2026Article
- Multilevel determinants of medication adherence among Chinese patients with chronic diseases: an ecological analysis based on the health ecology model.International journal of clinical pharmacy · 2026Article
- The impact of preoperative depressive symptoms on acute and chronic postoperative pain trajectories after orthopedic surgery for adolescent idiopathic scoliosis: a prospective cohort study.Journal of orthopaedic surgery and research · 2026Article
- Inflammatory score, intrinsic capacity and the risk of new-onset chronic lung disease: a cohort study from the China Health and Retirement Longitudinal Study.Journal of thoracic disease · 2026Article
- Late-life depression and risk of all-cause and cause-specific mortality in an Asian population: the Singapore Chinese Health Study.BMJ public health · 2026Article
- Activity-function transitions and interpretable machine learning for predicting incident depressive symptoms among ACE-exposed middle-aged and older adults: a multi-cohort study.Frontiers in public health · 2026Article
- The Mediating Role of Depression in the Effect of Psychological Well-Being on the Self-Rated Health and Quality of Life of Older Adults: Cross-Sectional Study.Interactive journal of medical research · 2025Article
- Multimorbidity Patterns and Depression: Bridging Epidemiological Associations with Predictive Analytics for Risk Stratification.Healthcare (Basel, Switzerland) · 2025Article
- Analysis of the Status and Influencing Factors of Depression in Chinese Middle-Aged and Older Cancer Patients-Based on Empirical Evidence from the 2020 CHARLS Database.Healthcare (Basel, Switzerland) · 2025Article
- Investigating the association between social participation and all-cause mortality risk among Chinese middle-aged and older adults.Frontiers in public health · 2025Article
- Interaction effects of sleep duration and activities of daily living on depressive symptoms among Chinese middle-aged and older adult individuals: evidence from the CHARLS.Frontiers in public health · 2025Article
- The impact of life events on health-related quality of life in rural older adults: the moderating role of social support.Frontiers in public health · 2025Article
- Gender disparities in healthy ageing in China: current status and future prospects.Frontiers in public health · 2025Article
- Using machine learning to predict depression among middle-aged and elderly population in China and conducting empirical analysis.PloS one · 2025Article
- Longitudinal Analysis of Risk Factors for Pulmonary Function Decline in Chronic Lung Diseases Over Five Years.International journal of chronic obstructive pulmonary disease · 2024Article
- Association of grip strength, sleep duration, and comorbidities with depressive symptoms in middle-aged and older patients with chronic lung diseases: a cross-sectional network analysis based on CHARLS data.Frontiers in psychology · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: It remains unclear whether depressive symptoms are associated with increased all-cause mortality and to what extent depressive symptoms are associated with chronic disease and all-cause mortality. The study aims to explore the relationship between depressive symptoms and all-cause mortality, and how depressive symptoms may, in turn, affect all-cause mortality among Chinese middle-aged and older people through chronic diseases. Methods: Data were collected from the China Health and Retirement Longitudinal Study (CHARLS). This cohort study involved 13,855 individuals from Wave 1 (2011) to Wave 6 (2020) of the CHARLS, which is a nationally representative survey that collects information from Chinese residents ages 45 and older to explore intrinsic mechanisms between depressive symptoms and all-cause mortality. The Center for Epidemiological Studies Depression Scale (CES-D-10) was validated through the CHARLS. Covariates included socioeconomic variables, living habits, and self-reported history of chronic diseases. Kaplan-Meier curves depicted mortality rates by depressive symptom levels, with Cox proportional hazards regression models estimating the hazard ratios (HRs) of all-cause mortality. Results: Out of the total 13,855 participants included, the median ( Conclusion: Depressive symptoms raise all-cause mortality risk, particularly in those aged 55 and above, rural household registration (agricultural Hukou), nonagricultural workers, and middle-aged and older people with hypertension, diabetes, and arthritis. Our findings through the longitudinal data collected in this study offer valuable insights for interventions targeting depression, such as early detection, integrated chronic disease care management, and healthy lifestyles; and community support for depressive symptoms may help to reduce mortality in middle-aged and older people.
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