Evidence map›Paper›PMID 38841513›Full record

ArticleHeliyon2024

Safety and efficacy evaluation of Simo decoction and

Jukai Huang, Yalu Wen, Tianyi Yang, Haibo Song, Ronald Meyboom, Xiaohui Yang, Lida Teng, Pierre Duez, Li Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jukai HuangDepartment of Endocrinology, Beijing University of Chinese Medicine, Dongzhimen Hospital, PR China.
Yalu WenDepartment of Respiratory Medicine, Beijing Hepingli Hospital, PR China.
Tianyi YangHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30329, United States.
Haibo SongCenter for Drug Reevaluation, National Medical Products Administration, Beijing, PR China.
Ronald MeyboomDepartment of Pharmacoepidemiology and Clinical Pharmacology, University of Utrecht, the Netherlands.
Xiaohui YangDepartment of Endocrinology, Beijing University of Chinese Medicine, Dongzhimen Hospital, PR China.
Lida TengDepartment of Health Economics and Outcomes Research, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Pierre DuezUnit of Therapeutic Chemistry and Pharmacognosy, Université de Mons (UMONS), Mons, Belgium.
Li ZhangDongfang Hospital Affiliated to Beijing University of Chinese Medicine, No. 6, District 1, Fangxingyuan, Fangzhuang, Fengtai District, Beijing, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The traditional Chinese patent medicine (TCPM), Simo decoction (Simo decoction oral solution), with its primary ingredient Methods: The study is based on post-marketing research of Simo decoction and Results: Common adverse drug reactions (ADRs) associated with Simo decoction include skin rash, nausea, vomiting, abdominal pain, and diarrhea. However, no studies exist reporting the severe ADRs, such as carcinogenic effects. Conclusion: Risk-benefit analysis in TCPM presents more challenges compared to conventional drugs. The development of a practical pharmacovigilance system and risk-benefit analysis framework is crucial for marketing authorization holders, researchers, and regulatory bodies. This approach is vital for scientific supervision and ensuring the safety and efficacy of drug applications, thus protecting public health.

Indexed as

Adverse reactionsArecae semenHerbal medicinePharmacovigilanceSimo decoctionTraditional Chinese medicine

Identifiers

PMID38841513
PMCPMC11152707

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.