Evidence map›Paper›PMID 38841113›Full record

ArticleFrontiers in cellular and infection microbiology2024

Kristie Goughenour, Arianna Creech, Jintao Xu, Xiumiao He, Rylan Hissong, Charles Giamberardino, Jennifer Tenor, Dena Toffaletti, John Perfect, Michal Olszewski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Cryptococcal nutrient acquisition and pathogenesis: dining on the host.Microbiology and molecular biology reviews : MMBR · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kristie GoughenourResearch Service, Lieutenant Colonel Charles S. Kettles VA Medical Center, Ann Arbor, MI, United States.
Arianna CreechResearch Service, Lieutenant Colonel Charles S. Kettles VA Medical Center, Ann Arbor, MI, United States.
Jintao XuResearch Service, Lieutenant Colonel Charles S. Kettles VA Medical Center, Ann Arbor, MI, United States.
Xiumiao HeResearch Service, Lieutenant Colonel Charles S. Kettles VA Medical Center, Ann Arbor, MI, United States.
Rylan HissongResearch Service, Lieutenant Colonel Charles S. Kettles VA Medical Center, Ann Arbor, MI, United States.
Charles GiamberardinoDivision of Infectious Diseases, Department of Medicine, Duke University, Durham, NC, United States.
Jennifer TenorDivision of Infectious Diseases, Department of Medicine, Duke University, Durham, NC, United States.
Dena ToffalettiDivision of Infectious Diseases, Department of Medicine, Duke University, Durham, NC, United States.
John PerfectDivision of Infectious Diseases, Department of Medicine, Duke University, Durham, NC, United States.
Michal OlszewskiResearch Service, Lieutenant Colonel Charles S. Kettles VA Medical Center, Ann Arbor, MI, United States.

Funding

PULMONARY CELLULAR AND MOLECULAR BIOLOGY TRAININGT32HL007749 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Robert Pickett Dickson · 1993 to 2026
$19.9M
Pathobiology of C. neoformans in the Central Nervous SystemR01AI073896 · NIAID · DUKE UNIVERSITY · PI PERFECT, JOHN R. · 2008 to 2018
$4.4M
Evolution of Cryptococcus neoformans Strains from Patients with HIV/AIDSR01AI093257 · NIAID · DUKE UNIVERSITY · PI PERFECT, JOHN R. · 2011 to 2022
$3.8M
Modulation of Pulmonary Defenses in Pathobiology of Chronic InfectionsI01BX000656 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2011 to 2025
–
BLRD Research Career Scientist Award ApplicationIK6BX005966 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2022 to 2025
–
BLRD VA I01 BX000656BLRD VA IK2 BX006208BLRD VA IK6 BX003615BLRD VA IK6 BX005966NHLBI NIH HHS T32 HL007749NIAID NIH HHS R01 AI073896NIAID NIH HHS R01 AI093257
6 · The paper itself

Abstract

Trehalose-6-phosphate synthase (TPS1) was identified as a virulence factor for

Indexed as

CryptococcosisCryptococcus neoformansDisease Models, AnimalGlucosyltransferasesLungVirulence FactorsAnimalsBrainGene DeletionHost-Pathogen InteractionsImmune EvasionImmunity, InnateMiceMice, Inbred C57BLSpleenVirulenceGlucosyltransferasestrehalose-6-phosphate synthaseVirulence FactorscapsuleCryptococcusdisseminatedpulmonaryTPS1trehalose

Identifiers

PMID38841113
PMCPMC11150607

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.