Evidence map›Paper›PMID 38841112›Full record

ArticleFrontiers in cellular and infection microbiology2024

Brooke A Hall, Kristen E Senior, Nicolle T Ocampo, Dhritiman Samanta

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Rab27: Molecular switch of tumor exosome secretion (Review).International journal of molecular medicine · 2026
    Review
  2. Article
  3. TFEB and MCOLN1 are important forFrontiers in cellular and infection microbiology · 2026
    Article
  4. Pathogen-induced rerouting of host membrane trafficking.Current opinion in cell biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brooke A HallDepartment of Microbiology and Immunology, College of Graduate Studies, Midwestern University, Glendale, AZ, United States.
Kristen E SeniorDepartment of Microbiology and Immunology, College of Graduate Studies, Midwestern University, Glendale, AZ, United States.
Nicolle T OcampoArizona College of Osteopathic Medicine, Midwestern University, Glendale, AZ, United States.
Dhritiman SamantaDepartment of Microbiology and Immunology, College of Graduate Studies, Midwestern University, Glendale, AZ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: We transfected HeLa cells with GFP-tagged Rab proteins and subsequently infected them with mCherry- Results: The CCV localization screen with host Rab proteins revealed that recycling endosome-associated proteins Rab11a and Rab35 localize to the CCV during infection, suggesting that CCV interacts with host recycling endosomes during maturation. Interestingly, only a subset of CCVs were Rab11a or Rab35-positive at any given time point. Quantitation of Rab11a/Rab35-positive CCVs revealed that while Rab11a interacts with the CCV more at 3 dpi, Rab35 is significantly more prevalent at CCVs at 6 dpi, suggesting that the CCV preferentially interacts with Rab11a and Rab35 depending on the stage of infection. Furthermore, we observed a significant increase in Rab11a and Rab35 fluorescent intensity in Discussion: Our data, for the first time, show that the CCV dynamically interacts with host recycling endosomes for

Indexed as

Coxiella burnetiiEndosomesHost-Pathogen Interactionsrab GTP-Binding ProteinsVacuolesHeLa CellsHumansQ Feverrab11 GTP-Binding Proteinsrab11 GTP-Binding ProteinsRAB35 protein, humanrab GTP-Binding Proteinsconfocal microscopyCoxiella burnetiiintracellular bacterial pathogenRab11aRab35recycling endosomes

Identifiers

PMID38841112
PMCPMC11150555

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.