Evidence map›Paper›PMID 38840975›Full record

ArticleFrontiers in surgery2024

Case Report: Low-grade glioma with

Joshua D Bernstock, Paramesh V Karandikar, Jason A Chen, Jakob Seidlitz, Gregory K Friedman, David M Meredith, Kevin X Liu, Daphne Haas-Kogan, David A Reardon, Pier Paolo Peruzzi

Abstract readCase Reports
In one paragraph

Article in Frontiers in surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joshua D Bernstock *Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA, United States.
Paramesh V Karandikar *Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA, United States.
Jason A ChenDepartment of Neurosurgery, Brigham and Women's Hospital, Boston, MA, United States.
Jakob SeidlitzDepartment of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Gregory K FriedmanDivision of Pediatrics, Neuro-Oncology Section, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
David M MeredithDepartment of Pathology, Brigham and Women's Hospital, Boston, MA, United States.
Kevin X LiuDepartment of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston Children's Hospital, Boston, MA, United States.
Daphne Haas-KoganDepartment of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston Children's Hospital, Boston, MA, United States.
David A ReardonDepartment of Medical Oncology, Center for Neuro-Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, MA, United States.
Pier Paolo PeruzziDepartment of Neurosurgery, Brigham and Women's Hospital, Boston, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrinsic, expansile pontine tumors typically occur in the pediatric population. These tumors characteristically present as diffuse intrinsic pontine glioma (DIPG), which is now considered as diffuse midline glioma (DMG), H3K27-mutated of the pons. DIPG has limited treatment options and a poor prognosis, and the value of tissue diagnosis from an invasive biopsy remains controversial. This study presents the case of a 19-year-old female with clinical and imaging hallmarks of DIPG, who underwent a biopsy of a tumor in the region of the right middle cerebellar peduncle. Her lesional cells were negative for H3K27M alterations and had low-grade histologic features. Next-generation sequencing revealed a frameshift mutation in the

Indexed as

biopsy-based diagnosisDIPGgliomaNF1pontine glioma

Identifiers

PMID38840975
PMCPMC11150652

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.