Evidence map›Paper›PMID 38840717›Full record

ArticleFrontiers in radiology2024

Standardized evaluation of the extent of resection in glioblastoma with automated early post-operative segmentation.

Lidia Luque, Karoline Skogen, Bradley J MacIntosh, Kyrre E Emblem, Christopher Larsson, David Bouget, Ragnhild Holden Helland, Ingerid Reinertsen, Ole Solheim, Till Schellhorn and 4 more

Abstract read
In one paragraph

Article in Frontiers in radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lidia LuqueComputational Radiology and Artificial Intelligence (CRAI), Department of Physics and Computational Radiology, Clinic for Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
Karoline SkogenDepartment of Radiology, Clinic for Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
Bradley J MacIntoshComputational Radiology and Artificial Intelligence (CRAI), Department of Physics and Computational Radiology, Clinic for Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
Kyrre E EmblemDepartment of Physics and Computational Radiology, Clinic for Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
Christopher LarssonInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
David BougetDepartment of Health Research, SINTEF Digital, Trondheim, Norway.
Ragnhild Holden HellandDepartment of Health Research, SINTEF Digital, Trondheim, Norway.
Ingerid ReinertsenDepartment of Health Research, SINTEF Digital, Trondheim, Norway.
Ole SolheimDepartment of Neurosurgery, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Till SchellhornComputational Radiology and Artificial Intelligence (CRAI), Department of Physics and Computational Radiology, Clinic for Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
Jonas VardalDepartment of Radiology, Clinic for Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
Eduardo E M MirelesInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Einar O Vik-MoInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Atle BjørnerudComputational Radiology and Artificial Intelligence (CRAI), Department of Physics and Computational Radiology, Clinic for Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Standard treatment of patients with glioblastoma includes surgical resection of the tumor. The extent of resection (EOR) achieved during surgery significantly impacts prognosis and is used to stratify patients in clinical trials. In this study, we developed a U-Net-based deep-learning model to segment contrast-enhancing tumor on post-operative MRI exams taken within 72 h of resection surgery and used these segmentations to classify the EOR as either maximal or submaximal. The model was trained on 122 multiparametric MRI scans from our institution and achieved a mean Dice score of 0.52 ± 0.03 on an external dataset (

Indexed as

deep-learningearly post-operativeextent of resectionglioblastomaMRIoverall survivalRANOsegmentation

Identifiers

PMID38840717
PMCPMC11150796

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.