Evidence map›Paper›PMID 38840199›Full record

ArticleTrials2024

Effectiveness of exercise rehabilitation on aplastic anemia patients receiving hematopoietic stem cell transplantation: study protocol for a randomized controlled trial.

Menghua Ye, Ting Liu, Xiaopei Mao, Xiaoxue Tan, Jin Wang, Min Xu

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06958380 (The Impact of Corrective Exercise and Rehabilitation on a Patient With Fanconi Anemia), which is not on this map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06958380 nacompletednot on this mapstarted 2025, after this paper: background citation

The Impact of Corrective Exercise and Rehabilitation on a Patient With Fanconi Anemia: A Clinical Case Study

TypeinterventionalSponsorPardis Specialized Wellness InstituteRan2025 to 2025Enrolled1ConditionsFanconi AnemiaArmsCorrective exercise and rehabilitation
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Menghua Ye *Department of Hematology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Ting Liu *The College of Nursing, Zhejiang Chinese Medical University, Hangzhou, China.
Xiaopei MaoDepartment of Hematology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Xiaoxue TanDepartment of Orthopedics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Jin WangDepartment of Rehabilitation, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Min XuDepartment of Nursing, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Shangcheng District, Hangzhou City, Zhejiang Province, People's Republic of China. yudi1212@163.com.ORCID http://orcid.org/0000-0002-7699-9792

Funding

Chinese Medicine Science and Technology Program Project of Zhejiang Province 2023ZL043
6 · The paper itself

Abstract

backgroundAlthough hematopoietic stem cell transplantation provides the chances of survival for aplastic anemia patients, it is also related to many treatment-related physical and psychological side effects that severely influence the quality of life. Exercise interventions have shown positive results in mixed hematology populations. The study aims to determine the effectiveness of exercise rehabilitation in improving the quality of life, fatigue, and physical function in these patients.

methodsThe study will enroll a total of 82 aplastic anemia patients receiving hematopoietic stem cell transplantation. They will be randomly divided into two groups in a 1:1 ratio. The intervention group will participate in structured exercise rehabilitation (plus usual care), while control group participants will receive usual care. The exercise rehabilitation program will be performed from neutrophil and platelet engraftment until 100 days after transplantation. All outcomes will be measured at the following time points: the neutrophil and platelet engraftment (± 1day, T0), discharge from the transplantation module (± 1 day, T1), hospital discharge (± 1 day, T2), and 100 days post-transplantation (± 5 days, T3). DISCUSSION: This study aims to assess the effectiveness of exercise rehabilitation for aplastic anemia patients receiving hematopoietic stem cell transplantation in a Chinese single center. It is particularly vital to conduct the studies in this population. Moreover, the evidence obtained from the study will provide evidence for future research and clinical practice to exercise in aplastic anemia patients.

trial registrationChiCTR2200060762. Registered on May 2022, www.trialregister.nl/trial/7702.

Indexed as

Anemia, AplasticExercise TherapyHematopoietic Stem Cell TransplantationQuality of LifeRandomized Controlled Trials as TopicAdolescentAdultChinaFatigueFemaleHumansMaleMiddle AgedRecovery of FunctionTime FactorsTreatment OutcomeAplastic anemiaEffectivenessExercise rehabilitationHematopoietic stem cell transplantationQuality of lifeRandomized controlled trial

Identifiers

PMID38840199
PMCPMC11151474

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