Evidence map›Paper›PMID 38840161›Full record

ArticleDiabetology & metabolic syndrome2024

Visceral fat area is more strongly associated with arterial stiffness than abdominal subcutaneous fat area in Chinese patients with type 2 diabetes.

Jing Mao, Shenglian Gan, Shijun Gong, Quan Zhou, Fang Yu, Haifeng Zhou, Huilin Lu, Qian Li, Zhiming Deng

Abstract read
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In one paragraph

Article in Diabetology & metabolic syndrome, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jing Mao *Department of Science and Education, Changde Hospital, Xiangya School of Medicine, Central South University, Changde, China.
Shenglian Gan *Department of Endocrinology, Changde Hospital, Xiangya School of Medicine, Central South University, Changde, China.
Shijun Gong *Department of Endocrinology, Changde Hospital, Xiangya School of Medicine, Central South University, Changde, China.
Quan ZhouDepartment of Science and Education, Changde Hospital, Xiangya School of Medicine, Central South University, Changde, China.
Fang YuDepartment of Endocrinology, Changde Hospital, Xiangya School of Medicine, Central South University, Changde, China.
Haifeng ZhouDepartment of Endocrinology, Changde Hospital, Xiangya School of Medicine, Central South University, Changde, China.
Huilin LuDepartment of Endocrinology, Changde Hospital, Xiangya School of Medicine, Central South University, Changde, China.
Qian LiDepartment of Pulmonary and Critical Care Medicine, Changde Hospital, Xiangya School of Medicine, Central South University, Changde, China.
Zhiming DengDepartment of Endocrinology, Changde Hospital, Xiangya School of Medicine, Central South University, Changde, China. 13974221766@163.com.

Funding

Hunan Provincial Key Laboratory of Clinical Epidemiology 2021ZNDXLCL001The Science and Technology Innovation Program of Changde City No. [2021]67
6 · The paper itself

Abstract

backgroundFew studies have compared the correlation between visceral fat area (VFA) and abdominal subcutaneous fat area (SFA) with arterial stiffness (AS) in patients with type 2 diabetes (T2D). In addition, there is currently controversy regarding the correlation between VFA and SFA with AS. We aimed to investigate the relationship between VFA and SFA with AS in patients with T2D.

methodsIn this cross-sectional study, 1475 Chinese T2D patients with an average age of 52.32 ± 10.96 years were included. VFA and SFA were determined by a dual bioelectrical impedance analyzer, and AS was determined by measurement of brachial-ankle pulse wave conduction velocity (baPWV). Atherosclerosis was deemed present in study participants with baPWV values higher than 75th percentile (1781 cm/s). Independent correlations of logVFA and logSFA with AS were assessed using multiple linear regression and multivariate logistic regression.

resultsThe baPWV was linked with VFA, waist circumference, and women's SFA in a general linear correlation study (P < 0.05), but not with body mass index (P = 0.3783) or men's SFA (P = 0.1899). In both men and women, VFA and SFA were positively correlated with AS, according to the generalized additive model (GAM). After fully adjusting for confounders, multiple linear regression analyses showed that for every 1-unit increase in logVFA, the beta coefficient of baPWV increased by 63.1 cm/s (95% CI: 18.4, 107.8) (P < 0.05). logSFA did not correlate significantly with baPWV (P = 0.125). In the multiple logistic regression analysis, the odds ratio (OR) of elevated baPWV was 1.8 (95% CI: 1.1, 3.1) (P = 0.019) per 1-unit increase in logVFA. logSFA did not correlate significantly with AS (P = 0.091). In the subgroup analysis, the correlation between logVFA and baPWV did not interact across subgroups (P-interaction > 0.05).

conclusionsCompared with SFA, VFA had a stronger independent positive correlation with AS in Chinese T2D patients. Patients with T2D should pay more attention to monitoring VFA and lowering it to minimize cardiovascular events.

Indexed as

Abdominal subcutaneous fat areaArterial stiffnessInsulin resistanceType 2 diabetesVisceral fat area

Identifiers

PMID38840161
PMCPMC11151495

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.