ArticleBMC gastroenterology2024
Mental health and quality of life in patients with chronic liver disease: a single-center structural equation model.
Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Resilience and physical-functional HRQoL in cirrhosis: a cross-sectional study of nursing-relevant direct and indirect associations linked to psychological distress and frailty.Scientific reports · 2026Article
- Latent class analysis of dyadic psychosocial adaptation in young and middle-aged couples with liver cirrhosis.Frontiers in psychology · 2026Article
- Global prevalence and predictors of depression and anxiety in patients with liver cirrhosis: a systematic review and meta-analysis.Frontiers in epidemiology · 2026Review
- Exploring the multidimensional value of midodrine-albumin synergistic therapy for refractory ascites.Hepatology international · 2025Article
- Nursing care for patients with liver cirrhosis undergoing surgery for esophageal variceal bleeding in an integrated healthcare system.World journal of gastrointestinal surgery · 2025Article
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7 authors.
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Abstract
backgroundChronic liver disease (CLD) is one of the leading disease burdens in Pakistan. Until now, there has only been limited focus in the country on providing health services through tertiary services in urban cities, whereas there is almost no research in Pakistan on the mental health and quality of life of CLD patients. This study aimed to understand which predictors influence the mental health and quality of life of CLD patients in order to advise better policy protection.
methodsData was collected from CLD patients at the Pakistan Kidney and Liver Institute and Research Centre, Lahore, Pakistan. A total of 850 respondents were part of the final sample. The age of respondents ranged from 18 to 79 years and included the following diagnosis: (i) Chronic Viral Hepatitis (n = 271), (ii) Cirrhosis (n = 259), (iii) Hepatocellular Carcinoma (n = 193), and (iv) Non-viral Liver Disease (n = 127).
resultsMean results reveal that females as well as illiterate patients need more support for mental health and communication with their physician; whereas men need more support to develop coping strategies. Structural equation modelling results reveal that the severity of symptoms (β = 0.24, p < 0.001), coping strategies (β=-0.51, p < 0.001), and doctor communication (β=-0.35, p < 0.001) predict mental health. Quality of life is associated with the severity of symptoms (β=-0.36, p < 0.001), coping strategies (β = 0.26, p < 0.05), and doctor communication (β = 0.09, p < 0.05).
conclusionsA 'bio-psycho-social-spiritual' model is recommended for Pakistan's CLD patients which includes the integration of social officers to provide support in four key areas to secure mental health and quality of life of patients.
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