ArticleNature2024
Myelin plasticity in the ventral tegmental area is required for opioid reward.
Abstract read
In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed.
- Inhibiting fear memory recall-induced oligodendrogenesis rescues PTSD-like behaviors.Molecular psychiatry · 2026Article
- Rethinking the Oligodendrocyte Progenitor Cell: One Cell, Many Functions.The European journal of neuroscience · 2026Review
- Mesocorticolimbic Dopamine-Reward Tract Alterations and the 'Dark Side' of Methamphetamine Addiction.Addiction biology · 2026Article
- Spontaneous oxycodone withdrawal alters behavior and oligodendrocyte-related gene expression in mice.Pharmacology, biochemistry, and behavior · 2026Article
- Chronic morphine differentially impacts glutamatergic synaptic plasticity in the ventral tegmental area of adult versus adolescent mice.Neuropharmacology · 2026Article
- The actions of morphine on microglia and the underlying effects on associated adverse effects.Psychopharmacology · 2026Review
- Substance abuse and inflammation: consequences beyond the brain.Trends in immunology · 2026Review
- Spared Nerve Injury Induces Long-Term and Brain Region-Specific Changes in Oligodendrocyte Density in Mice.European journal of pain (London, England) · 2026Article
- Brain-wide mapping of oligodendrocyte organization, oligodendrogenesis, and myelin injury.Cell · 2026Article
- Changes in Blood DNA CpG Methylation Levels in Response to Methadone Maintenance Treatment: Epigenome-Wide Longitudinal Study.Epigenomes · 2026Article
- Photobiomodulation and Addiction: Exploring Mechanisms, Therapeutic Potential, and Future Directions in Substance Use Disorders.Neuroscience bulletin · 2026Article
- Astragaloside II, a natural saponin, facilitates remyelination in demyelination neurological diseases via p75NTR receptor mediated β-catenin/Id2/MBP signaling axis in oligodendrocyte precursor cells.Journal of advanced research · 2026Article
- Myelin Lipid Reserves as a Conditional Metabolic Buffer: Implications for Alzheimer's Disease and Ischemic Stroke.Neuromolecular medicine · 2026Review
- Renewal and reacquisition of substance-associated relapse.Frontiers in psychology · 2026Review
- Inhibited oligodendrogenesis impairs attention and motivation in adult mice regardless of repeated mild traumatic brain injury.Frontiers in behavioral neuroscience · 2026Article
- Dysregulated Microglial Synaptic Engulfment in Diffuse Midline Glioma.bioRxiv : the preprint server for biology · 2025Article
- The neural circuits and signalling pathways of opioid use disorder.Nature reviews. Neuroscience · 2025Review
- Dissociable Neural Connectome Mapping of Reward and Punishment Responsiveness in Young Adults: Associations with Genetic Variability and Neurotransmitter Profiles.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Current states in understanding oligodendroglia-mediated neurological issues in neurofibromatosis type 1 (NF1).Acta neuropathologica communications · 2025Review
- Morphine regulates astrocyte transcriptional dynamics in the ventral tegmental area by stimulation of glucocorticoid signaling.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Belgin YalçınDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0001-9689-9062
Matthew B PomrenzeNancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0002-9032-5911
Karen MalaconDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Richard DrexlerDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Abigail E RogersDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Kiarash ShamardaniDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0002-2548-705X
Isabelle J ChauDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0003-3733-4760
Kathryn R TaylorDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0002-5110-8703
Lijun NiDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Daniel Contreras-EsquivelDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Robert C MalenkaNancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0002-5428-5211
Michelle MonjeDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA. mmonje@stanford.edu.ORCID 0000-0002-3547-237X
Funding
Targeting the Vasular SystemP50CA165962 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Benjamin Harris Kann · 2013 to 2026
$33.5MTraining CoreP50DA042012 · NIDA · STANFORD UNIVERSITY · PI Karl A. Deisseroth, Lisa Giocomo · 2017 to 2026
$27.1MLeveraging innovative technologies in basic and clinical cancer researchT32CA009302 · NCI · STANFORD UNIVERSITY · PI LAURA D ATTARDI, Aaron M Newman · 1985 to 2026
$19.1MMedical Scientist Training ProgramT32GM145402 · NIGMS · STANFORD UNIVERSITY · PI Katrin F. Chua · 2022 to 2026
$10.0MeDyNAmiC - STANFORDOT2CA278688 · NCI · STANFORD UNIVERSITY · PI PAUL S MISCHEL · 2022 to 2026
$7.7MInterdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2MTargeting the neuronal microenvironment in glioblastomaU19CA264504 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI Tracy T Batchelor · 2021 to 2026
$6.4MGlioma Circuitry: Bridging Systems Neuroscience and CancerDP1NS111132 · NINDS · STANFORD UNIVERSITY · PI MONJE-DEISSEROTH, MICHELLE · 2018 to 2022
$5.7MNeuronal Regulation of Low-Grade GliomagenesisR01CA258384 · NCI · STANFORD UNIVERSITY · PI David H Gutmann, Michelle Monje-Deisseroth · 2022 to 2026
$3.1MNeuronal activity-regulated mechanisms of glioma growthR01NS092597 · NINDS · STANFORD UNIVERSITY · PI MONJE-DEISSEROTH, MICHELLE · 2016 to 2021
$2.1MModulation of protracted opioid withdrawal by dorsal raphe dynorphin neuronsK99DA056573 · NIDA · STANFORD UNIVERSITY · PI POMRENZE, MATTHEW B · 2022 to 2023
$317kNCI NIH HHS OT2 CA278688NCI NIH HHS P50 CA165962NCI NIH HHS R01 CA258384NCI NIH HHS T32 CA009302NCI NIH HHS U19 CA264504NIDA NIH HHS K99 DA056573NIDA NIH HHS P50 DA042012NIDA NIH HHS T32 DA035165NIGMS NIH HHS T32 GM145402NINDS NIH HHS DP1 NS111132NINDS NIH HHS R01 NS092597
Abstract
All drugs of abuse induce long-lasting changes in synaptic transmission and neural circuit function that underlie substance-use disorders
Indexed as
Analgesics, OpioidMyelin SheathNeural PathwaysNeuronal PlasticityRewardVentral Tegmental AreaAnimalsCell LineageDopamineDopaminergic NeuronsFemaleGABAergic NeuronsMaleMiceMice, Inbred C57BLMorphineAnalgesics, OpioidDopamineMorphine
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.