Evidence map›Paper›PMID 38839956›Full record

ArticleNature2024

Profiling phagosome proteins identifies PD-L1 as a fungal-binding receptor.

Kai Li, Avradip Chatterjee, Chen Qian, Katherine Lagree, Yang Wang, Courtney A Becker, Michael R Freeman, Ramachandran Murali, Wei Yang, David M Underhill

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Innate immune recognition ofInfection and immunity · 2026
    Article
  3. Article
  4. Article
  5. Proton-activated chloride channel 1 is essential for innate host defense against bacterial sepsis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. CD14Frontiers in cellular and infection microbiology · 2025
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kai LiDepartment of Biomedical Sciences, Division of Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, USA. zach.lee.2008@gmail.com.ORCID 0000-0003-3329-8125
Avradip ChatterjeeDepartment of Biomedical Sciences, Division of Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0001-8345-4339
Chen QianDepartment of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Katherine LagreeDepartment of Biomedical Sciences, Division of Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0003-1430-3312
Yang WangDepartment of Biomedical Sciences, Division Cancer Biology and Therapeutics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0003-4106-6893
Courtney A BeckerF. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Michael R FreemanDepartment of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0001-8142-3432
Ramachandran MuraliDepartment of Biomedical Sciences, Division of Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0002-8384-2793
Wei YangDepartment of Biomedical Sciences, Division Cancer Biology and Therapeutics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0003-2575-3570
David M UnderhillDepartment of Biomedical Sciences, Division of Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, USA. David.Underhill@csmc.edu.ORCID 0000-0002-2989-658X

Funding

Non-Toll-like receptor innate immune signalingR01AI071116 · NIAID · CEDARS-SINAI MEDICAL CENTER · PI UNDERHILL, DAVID M. · 2008 to 2023
$6.3M
NIAID NIH HHS R01 AI071116
6 · The paper itself

Abstract

Phagocytosis is the process by which myeloid phagocytes bind to and internalize potentially dangerous microorganisms

Indexed as

B7-H1 AntigenFungal ProteinsPhagosomesRibosomal ProteinsSaccharomyces cerevisiaeAnimalsEscherichia coliFemaleHost Microbial InteractionsHumansImmunity, InnateInterleukin-10LigandsMacrophagesMaleMiceB7-H1 AntigenCD274 protein, humanFungal ProteinsInterleukin-10LigandsRibosomal Proteins

Identifiers

PMID38839956
PMCPMC12755075

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.