ArticleNature2024
MYCT1 controls environmental sensing in human haematopoietic stem cells.
Abstract read
In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- JARID2 inhibition reprograms human hematopoietic progenitor cells to enhance bone marrow transplantation.Blood advances · 2026Article
- MYCT1-IFITM2/3 interaction links endothelial endolysosomal trafficking to white adipose tissue expansion.The Journal of experimental medicine · 2026Article
- Article
- Elevated endocytic trafficking mediated by GPRASP2 maintains HSC fidelity.bioRxiv : the preprint server for biology · 2026Article
- CRISPR-based therapeutic genome editing for inherited blood disorders.Nature reviews. Drug discovery · 2025Review
- Reconstruction of hematopoietic stem cell nichesMaterials today. Bio · 2025Review
- JARID2 Inhibition Reprograms Human Hematopoietic Progenitor Cells To Enhance Bone Marrow Transplantation.bioRxiv : the preprint server for biology · 2025Article
- Chirality Regulates Stem Cell Fate and Promotes Corneal Epithelial Regeneration via Manipulating Notch Pathway.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Transcriptional and chromatin accessibility landscapes of hematopoiesis in a mouse model of breast cancer.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Article
- FoxO1 regulates human haematopoietic stem cells self-renewal and engraftment.Molecular biology reports · 2024Article
- Molecular characterization of human HSPCs with different cell fates in vivo using single-cell transcriptome analysis and lentiviral barcoding technology.Clinical and translational medicine · 2024Article
- Endocytosis as a critical regulator of hematopoietic stem cell fate -implications for hematopoietic stem cell and gene therapy.Stem cell research & therapy · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Júlia Aguadé-GorgorióDepartment of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA. julia.aguade@gmail.com.ORCID 0000-0001-5600-4279
Yasaman Jami-AlahmadiDepartment of Biological Chemistry, University of California Los Angeles, Los Angeles, CA, USA.
Vincenzo CalvaneseDepartment of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-7937-1511
Maya KardouhDepartment of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Iman FaresDepartment of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Haley JohnsonDepartment of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Valerie RezekEli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-2336-7599
Feiyang MaDepartment of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-6260-0787
Mattias MagnussonDepartment of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Yanling WangDepartment of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Juliana E ShinBoard of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Karina J NanceBoard of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Helen S GoodridgeDavid Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Simone LiebscherInstitute of Biomedical Engineering, Department for Medical Technologies and Regenerative Medicine, Eberhard Karls University, Tübingen, Germany.
Katja Schenke-LaylandInstitute of Biomedical Engineering, Department for Medical Technologies and Regenerative Medicine, Eberhard Karls University, Tübingen, Germany.ORCID 0000-0001-8066-5157
Gay M CrooksEli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-2488-8468
James A WohlschlegelDepartment of Biological Chemistry, University of California Los Angeles, Los Angeles, CA, USA.
Hanna K A MikkolaDepartment of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA. hmikkola@mcdb.ucla.edu.ORCID 0000-0002-3400-1496
Funding
Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5MUCLA-CDU CFARP30AI152501 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Homero Erwin del Pino · 2022 to 2026
$15.6MTraining in Developmental HematologyT32HL086345 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KOHN, DONALD B · 2007 to 2022
$3.8MDefining the Self-Renewal Program in Human Hematopoietic Stem CellsR01DK100959 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MIKKOLA, HANNA KATRI ANNIKKI · 2014 to 2022
$2.9MREGULATION OF HUMAN HEMATOPOIETIC STEM CELL FATE VIA MLLT3 ISOFORMSR01DK121557 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Hanna Katri Annikki Mikkola · 2019 to 2026
$2.3MUnderstanding Ubiquitin-dependent Regulation of Iron Metabolism using Mass SpectrometryR35GM153408 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI James Akira Wohlschlegel · 2024 to 2026
$1.2MMYCT1 as a moderator for signaling between human HSC and their nicheR01HL162408 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MIKKOLA, HANNA KATRI ANNIKKI · 2022 to 2024
$936kMapping human hematopoietic stem cell developmentR01DK125097 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MIKKOLA, HANNA KATRI ANNIKKI · 2021 to 2023
$917kNCI NIH HHS P30 CA016042NHLBI NIH HHS R01 HL162408NHLBI NIH HHS T32 HL086345NIAID NIH HHS P30 AI152501NIDDK NIH HHS R01 DK100959NIDDK NIH HHS R01 DK121557NIDDK NIH HHS R01 DK125097NIGMS NIH HHS R35 GM153408Wellcome Trust
Abstract
The processes that govern human haematopoietic stem cell (HSC) self-renewal and engraftment are poorly understood and challenging to recapitulate in culture to reliably expand functional HSCs
Indexed as
Cell Self RenewalHematopoietic Stem CellsNuclear ProteinsAnimalsCells, CulturedEndocytosisEndosomesEndothelial CellsFemaleFetal BloodGene Knockdown TechniquesHumansLiverMaleMiceMitochondriaMYCT1 protein, humanNuclear ProteinsProto-Oncogene Proteins c-ets
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.