Evidence map›Paper›PMID 38839848›Full record

ArticleScientific reports2024

Dysbiosis not observed in Canadian horse with free fecal liquid (FFL) using 16S rRNA sequencing.

Robert J Wester, Lyndsey L Baillie, Garrett C McCarthy, Carson C Keever, Lauren E Jeffery, Paul J Adams

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robert J WesterApplied Genomics Centre, Kwantlen Polytechnic University, Surrey, BC, Canada.
Lyndsey L BaillieApplied Genomics Centre, Kwantlen Polytechnic University, Surrey, BC, Canada.
Garrett C McCarthyApplied Genomics Centre, Kwantlen Polytechnic University, Surrey, BC, Canada.
Carson C KeeverFaculty of Science, Kwantlen Polytechnic University, Surrey, BC, Canada.
Lauren E JefferyAgwest Veterinary Group Ltd., Abbotsford, BC, Canada.
Paul J AdamsApplied Genomics Centre, Kwantlen Polytechnic University, Surrey, BC, Canada. paul.adams@kpu.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Free Fecal Liquid (FFL), also termed Fecal Water Syndrome (FWS), is an ailment in horses characterized by variable solid and liquid (water) phases at defecation. The liquid phase can be excreted before, during, or after the solid defecation phase. While the underlying causes of FFL are unknown, hindgut dysbiosis is suggested to be associated with FFL. Three European studies investigated dysbiosis in horses with FFL using 16S rRNA sequencing and reported results that conflicted between each other. In the present study, we also used 16S rRNA sequencing to study the fecal microbial composition in 14 Canadian horses with FFL, and 11 healthy stable mate controls. We found no significant difference in fecal microbial composition between FFL and healthy horses, which further supports that dysbiosis is not associated with FFL.

Indexed as

DysbiosisFecesRNA, Ribosomal, 16SAnimalsCanadaFemaleGastrointestinal MicrobiomeHorse DiseasesHorsesMaleRNA, Ribosomal, 16S

Identifiers

PMID38839848
PMCPMC11153561

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.