Evidence map›Paper›PMID 38839789›Full record

ArticleScientific data2024

Whole genome sequences of 70 indigenous Ethiopian cattle.

Wondossen Ayalew, Wu Xiaoyun, Getinet Mekuriaw Tarekegn, Rakan Naboulsi, Tesfaye Sisay Tessema, Renaud Van Damme, Erik Bongcam-Rudloff, Min Chu, Chunnian Liang, Zewdu Edea and 2 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wondossen Ayalew *Key Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Key Laboratory of Yak Breeding Engineering, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou, 730050, P.R. China.
Wu Xiaoyun *Key Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Key Laboratory of Yak Breeding Engineering, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou, 730050, P.R. China.
Getinet Mekuriaw TarekegnInstitute of Biotechnology, Addis Ababa University, Addis Ababa P.O. Box 1176, Addis Ababa, Ethiopia. Getinet.Tarekegn@sruc.ac.uk.
Rakan NaboulsiChildhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institute, Tomtebodavägen 18A, 17177, Stockholm, Sweden.
Tesfaye Sisay TessemaInstitute of Biotechnology, Addis Ababa University, Addis Ababa P.O. Box 1176, Addis Ababa, Ethiopia.
Renaud Van DammeDepartment of Animal Biosciences, Swedish University of Agricultural Sciences, 75007, Uppsala, Sweden.ORCID 0000-0002-7909-4868
Erik Bongcam-RudloffDepartment of Animal Biosciences, Swedish University of Agricultural Sciences, 75007, Uppsala, Sweden.ORCID 0000-0002-1947-8288
Min ChuKey Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Key Laboratory of Yak Breeding Engineering, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou, 730050, P.R. China.
Chunnian LiangKey Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Key Laboratory of Yak Breeding Engineering, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou, 730050, P.R. China.
Zewdu EdeaEthiopian Bio and Emerging Technology Institute, Addis Ababa, Ethiopia.
Solomon EnquahoneScotland's Rural College (SRUC), Roslin Institute Building, University of Edinburgh, Edinburgh, EH25 9RG, UK.
Yan PingKey Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Key Laboratory of Yak Breeding Engineering, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou, 730050, P.R. China. pingyanlz@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indigenous animal genetic resources play a crucial role in preserving global genetic diversity and supporting the livelihoods of millions of people. In Ethiopia, the majority of the cattle population consists of indigenous breeds. Understanding the genetic architecture of these cattle breeds is essential for effective management and conservation efforts. In this study, we sequenced DNA samples from 70 animals from seven indigenous cattle breeds, generating about two terabytes of pair-end reads with an average coverage of 14X. The sequencing data were pre-processed and mapped to the cattle reference genome (ARS-UCD1.2) with an alignment rate of 99.2%. Finally, the variant calling process produced approximately 35 million high-quality SNPs. These data provide a deeper understanding of the genetic landscape, facilitate the identification of causal mutations, and enable the exploration of evolutionary patterns to assist cattle improvement and sustainable utilization, particularly in the face of unpredictable climate changes.

Indexed as

CattleGenomePolymorphism, Single NucleotideWhole Genome SequencingAnimalsBreedingEthiopia

Identifiers

PMID38839789
PMCPMC11153504

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.