Evidence map›Paper›PMID 38839639›Full record

ArticleJournal of neurology2024

Neck rigidity: a pitfall for video head-impulse tests in Parkinson's disease.

Donghoon Woo, Yukang Kim, Kyoungwon Baik, Sun-Uk Lee, Euyhyun Park, Chan-Nyoung Lee, Seoui Kwag, Hyunsoh Park, Ji-Soo Kim, Kun-Woo Park

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In one paragraph

Article in Journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Donghoon WooNeurotology and Neuro-ophthalmology Laboratory, Korea University Medical Center, Seoul, South Korea.
Yukang KimNeurotology and Neuro-ophthalmology Laboratory, Korea University Medical Center, Seoul, South Korea.
Kyoungwon BaikDepartment of Neurology, Korea University Medical Center, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea.
Sun-Uk LeeNeurotology and Neuro-ophthalmology Laboratory, Korea University Medical Center, Seoul, South Korea. sulee716@gmail.com.ORCID http://orcid.org/0000-0001-8660-7759
Euyhyun ParkNeurotology and Neuro-ophthalmology Laboratory, Korea University Medical Center, Seoul, South Korea.
Chan-Nyoung LeeDepartment of Neurology, Korea University Medical Center, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea.
Seoui KwagNeurotology and Neuro-ophthalmology Laboratory, Korea University Medical Center, Seoul, South Korea.
Hyunsoh ParkNeurotology and Neuro-ophthalmology Laboratory, Korea University Medical Center, Seoul, South Korea.
Ji-Soo KimDepartment of Neurology, Seoul National University College of Medicine, Seoul, South Korea.
Kun-Woo ParkDepartment of Neurology, Korea University Medical Center, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea.

Funding

Ministry of Science and ICT, South Korea 2022R1A4A1018869
6 · The paper itself

Abstract

Video head impulse tests (video-HITs) are commonly used for vestibular evaluation; however, the results can be contaminated by various artifacts, including technical errors, recording problems, and participant factors. Although video-HITs can be used in patients with Parkinson's disease (PD), the effect of neck rigidity has not been systematically investigated. This study aimed to investigate the effect of neck rigidity on video-HIT results in patients with PD. We prospectively recruited 140 consecutive patients with PD (mean age ± standard deviation = 68 ± 10 years, 69 men) between September 2021 and April 2024 at Korea University Medical Center. The video-HIT results were compared with those of 19 age- and sex-matched healthy participants. Neck rigidity was stratified as a subdomain of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale motor part (MDS-UPDRS-III). In 59 patients, the vestibulo-ocular reflex (VOR) gain was overestimated in at least one canal plane (58/140, 41%), mostly in the anterior canal (AC, n = 44), followed by the horizontal (HC, n = 15) and posterior canals (PC, n = 7). VOR gain overestimation was also observed in patients with no (18/58, 35%), subtle (20/58, 34%), or mild (17/58, 29%) neck rigidity. Multivariable logistic regression analysis showed that VOR overestimation was positively associated with neck rigidity (odds ratio [OR] [95% confidence interval] = 1.51 [1.01-2.25], p = 0.043). The head velocities of patients decreased during head impulses for the AC (p = 0.033 for the right AC; p = 0.014 for the left AC), whereas eye velocities were similar to those of healthy participants. Our findings suggest that neck rigidity may be a confounder that can contaminate video-HIT results. Thus, the results of video-HITs, especially for the AC, should be interpreted with the context of head velocity during head impulses in patients with neck rigidity.

Indexed as

Head Impulse TestMuscle RigidityParkinson DiseaseReflex, Vestibulo-OcularVideo RecordingAgedFemaleHumansMaleMiddle AgedNeck MusclesProspective StudiesHead-impulse testParkinson’s diseaseRigidityVertigo

Identifiers

PMID38839639

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.