Evidence map›Paper›PMID 38839628›Full record

ReviewInflammation research : official journal of the European Histamine Research Society ... [et al.]2024

The role of regulatory T cells in vitiligo and therapeutic advances: a mini-review.

Shiyu Jin, Sheng Wan, Renxue Xiong, Yujie Li, Tingru Dong, Cuiping Guan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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  9. Exploring New Frontiers: Innovations and Therapeutic Targets in Dermatology.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shiyu JinHangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, 310009, China.
Sheng WanHangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, 310009, China.
Renxue XiongHangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, 310009, China.
Yujie LiHangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, 310009, China.
Tingru DongHangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, 310009, China.
Cuiping GuanHangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, 310009, China. imgcp@zcmu.edu.cn.

Funding

Hangzhou medical key discipline construction project No. [2021]21-3Zhejiang medical and health science and technology project No. 2021KY903Zhejiang Provincial Natural Science Foundation of China No. LY21H110001
6 · The paper itself

Abstract

backgroundRegulatory T cells (Tregs) play vital roles in controlling immune reactions and maintaining immune tolerance in the body. The targeted destruction of epidermal melanocytes by activated CD8

methodsA comprehensive search of PubMed and Web of Science was conducted to gather information on Tregs and vitiligo.

resultsIn vitiligo, there is a decrease in Treg numbers and impaired Treg functions, along with potential damage to Treg-related signaling pathways. Increasing Treg numbers and enhancing Treg function could lead to immunosuppressive effects on CD8

conclusionsA deeper understanding of Tregs will be crucial for advancing Treg-related drug discovery and treatment development in vitiligo.

Indexed as

VitiligoAnimalsAutoantigensDrug DiscoveryHumansReceptors, ChemokineSignal TransductionAutoantigensReceptors, ChemokineCD4+ T cellsCD8+ T cellsTherapyTregsVitiligo

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.