Evidence map›Paper›PMID 38839517›Full record

ArticleVaccine2024

Costs of in- and outpatient respiratory disease and the seasonal influenza vaccination program in Armenia - 2020-2021.

Stacie Gobin, Gayane Sahakyan, Michael Kusi Appiah, Ani Manukyan, Karo Palayan, Malembe Ebama, Artavazd Vanyan, Margaret McCarron, Joseph Bresee

Abstract read
In one paragraph

Article in Vaccine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stacie GobinGobin Global, LLC, Asheville, NC, USA. Electronic address: stacieg@gobin-global.com.
Gayane SahakyanNational Center for Disease Control and Prevention, Ministry of Health, Yerevan, Armenia.
Michael Kusi AppiahGobin Global, LLC, Asheville, NC, USA.
Ani ManukyanNational Center for Disease Control and Prevention, Ministry of Health, Yerevan, Armenia.
Karo PalayanNational Center for Disease Control and Prevention, Ministry of Health, Yerevan, Armenia.
Malembe EbamaTask Force for Global Health, Decatur, GA, USA.
Artavazd VanyanNational Center for Disease Control and Prevention, Ministry of Health, Yerevan, Armenia.
Margaret McCarronU.S. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Joseph BreseeTask Force for Global Health, Decatur, GA, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundDespite the substantial global impact of influenza, there are limited economic data to guide influenza vaccination programs investments in middle-income countries. We measured the costs of influenza and the costs of an influenza vaccination program in Armenia, using a societal perspective.

methodsDuring December 2022 through March 2023, retrospective cost data were collected from case-patients and healthcare providers through structured questionnaires at 15 healthcare facilities selected through stratified sampling. Medical costs included medications, laboratory costs, laboratory and diagnostic tests, and routine health care service costs and direct and indirect societal costs were included. Vaccination program costs from the 2021-2022 influenza season were identified using accounting records and categorized as: planning, distribution, training, social mobilization and outreach, supervision and monitoring, procurement, and national- and facility-level administration and storage.

resultsThe mean costs per episode for SARI and ILI case-patients were $US 823.6 and $US 616.57, respectively. Healthcare service costs were the largest direct expenses for ILI and SARI case-patients. Total costs of the 2021-2022 influenza vaccination program to the government were $US 4,353,738, with the largest costs associated with national- and facility-level administration and storage (30% and 65% respectively). The total cost per dose administered was $US 25.61 ($US 7.73 per dose for procurement and $US 17.88 for the marginal administration cost per dose).

conclusionsThese data on the costs of seasonal influenza prevention programs and the societal costs of influenza illness in Armenia may inform national vaccine policy decisions in Armenia and may be useful for other middle-income countries. Influenza vaccines, like other vaccine programs, are recognized as substantially contributing to the reduction disease burden and associated mortality and further driving economic growth. However, a formal cost-effectiveness analysis should be performed once burden of disease data are available.

Indexed as

Health Care CostsImmunization ProgramsInfluenza, HumanInfluenza VaccinesOutpatientsVaccinationAdolescentAdultAgedArmeniaChildChild, PreschoolFemaleHumansInfantMaleInfluenza VaccinesArmeniaCost-effectivenessCostingInfluenzaVaccinationVaccination program

Identifiers

PMID38839517
PMCPMC11464208

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.