Evidence map›Paper›PMID 38839300›Full record

ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2025

Relationship between Pulmonary Gas Exchange Function and Brain Uptake Dynamics Investigated with Hyperpolarized

Atsuomi Kimura, Akihiro Shimokawa, Neil J Stewart, Hirohiko Imai, Hideaki Fujiwara

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Atsuomi KimuraDepartment of Medical Physics and Engineering, Area of Medical Imaging Technology and Science, Division of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.ORCID http://orcid.org/0000-0001-5702-276X
Akihiro ShimokawaDepartment of Medical Physics and Engineering, Area of Medical Imaging Technology and Science, Division of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
Neil J StewartPOLARIS, Division of Clinical Medicine, School of Medicine and Population Health, Faculty of Health, University of Sheffield, Sheffield, United Kingdom.ORCID http://orcid.org/0000-0001-8358-394X
Hirohiko ImaiDivision of Systems Informatics, Department of Systems Science, Graduate School of Informatics, Kyoto University, Kyoto, Kyoto, Japan.
Hideaki FujiwaraDepartment of Medical Physics and Engineering, Area of Medical Imaging Technology and Science, Division of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.ORCID http://orcid.org/0000-0002-9720-3546

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChronic obstructive pulmonary disease (COPD) is a complex multisystem disease associated with comorbidities outside the lungs. The aim of this study was to measure changes in metrics of pulmonary gas exchange function and brain tissue metabolism in a mouse model of COPD using hyperpolarized

methodsCOPD phenotypes were induced in 15 mice by 6-week administration of cigarette smoke extract (CSE) and lipopolysaccharide (LPS). A separate negative control (NC) group was formed of 6 mice administered with saline for 6 weeks. After these 6-week administrations, the pulmonary gas exchange function parameter f

resultsThe f

conclusionThis study demonstrates the feasibility of using HP

Indexed as

BrainMagnetic Resonance ImagingPulmonary Disease, Chronic ObstructivePulmonary Gas ExchangeXenon IsotopesAnimalsDisease Models, AnimalLungMagnetic Resonance SpectroscopyMaleMiceMice, Inbred C57BLXenon-129Xenon Isotopesbrain uptake dynamicshyperpolarized 129Xemurine chronic obstructive pulmonary diseasepulmonary gas exchange function

Identifiers

PMID38839300
PMCPMC12406161

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.