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ArticleNeurologia medico-chirurgica2024

Trends and Progress in Neuroendovascular Treatment in Japan: Japanese Registry of Neuroendovascular Therapy (JR-NET) 4. Main Report.

Nobuyuki Sakai, Satoru Fujiwara, Kazutaka Uchida, Koji Iihara, Hirotoshi Imamura, Akira Ishii, Yuji Matsumaru, Chiaki Sakai, Tetsu Satow, Shinichi Yoshimura and 9 more

Abstract readMulticenter Study
In one paragraph

Article in Neurologia medico-chirurgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Nobuyuki SakaiDepartment of Neurovascular Research, Kobe City Medical Center General Hospital.
Satoru FujiwaraDepartment of Neurovascular Research, Kobe City Medical Center General Hospital.
Kazutaka UchidaDepartment of Neurosurgery, Hyogo Medical University.
Koji IiharaDepartment of Neurosurgery, National Cerebral and Cardiovascular Center.
Hirotoshi ImamuraDepartment of Neurosurgery, National Cerebral and Cardiovascular Center.
Akira IshiiDepartment of Neurosurgery, Kyoto University.
Yuji MatsumaruDepartment of Neurosurgery, University of Tsukuba.
Chiaki SakaiDepartment of Neurovascular Research, Kobe City Medical Center General Hospital.
Tetsu SatowDepartment of Neurosurgery, Kindai University.
Shinichi YoshimuraDepartment of Neurosurgery, Hyogo Medical University.
Yasushi MatsumotoDepartment of Neurosurgery, Konan Hospital.
Hidenori OishiDepartment of Neurosurgery, Juntendo University.
Naoto KimuraDepartment of Neurosurgery, Iwate Prefectural Central Hospital.
Masayuki EzuraDepartment of Neurosurgery, National Hospital Organization Sendai Medical Center.
Tatsufumi NomuraDepartment of Neurosurgery, Sapporo Shiroishi Memorial Hospital.
Shinzo OtaDepartment of Neurosurgery, Ota Memorial Hospital.
Akio HyodoDepartment of Neurosurgery, Dokkyo University Saitama Medical Center.
Fuminori ShimizuDepartment of Neurosurgery, Seijinkai Shimizu Hospital.
Japanese Registry of Neuroendovascular Therapy (JR-NET) Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We reported the main results of the Japanese Registry of Neuroendovascular Therapy (JR-NET) 4, a nationwide surveillance of therapy (NET) in Japan from January 2015 to December 2019. JR-NET 4 registered consecutive patients who underwent NETs by Japan Society of Neuroendovascular Therapy (JSNET) -certified specialists. The primary endpoint was functional independence (mRS score of 0-2) at 30 days post-NET, with secondary endpoints focusing on technical success and major adverse events within 30 days.A total of 63,230 patients and 60,354 NET procedures from 166 participating centers were analyzed. During the study period, NET cases have consistently increased, with an increase in the proportion of elderly patients. A significant trend shift was observed in the distribution of NET procedures, with endovascular treatment for acute ischemic stroke that showed a dramatic increase in 5 years. This trend aligns with key randomized clinical trials from 2015 that presented the efficacy of this treatment. Clinical outcomes at 30 days posttreatment revealed that endovascular treatment for acute ischemic stroke and other NETs maintained safety and effectiveness despite varying prevalence of functional independence between target diseases. The study also observed a steady increase in emergency treatment cases, reflecting the increase in acute ischemic stroke, a time-sensitive medical condition.This comprehensive surveillance highlights the trend of NET practices in Japan, driven by clinical evidence and advancements in treatment devices. Although these findings were specific to Japan, they offer valuable insights into the broader trends in NETs and acute stroke care.

Indexed as

Endovascular ProceduresIschemic StrokeRegistriesAgedAged, 80 and overEast Asian PeopleFemaleHumansJapanMaleMiddle AgedTreatment Outcomeclinical outcomeendovascular treatmentnationwide surveillanceregistry studysafety endpoint

Identifiers

PMID38839294
PMCPMC11374464

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.