Evidence map›Paper›PMID 38839285›Full record

ReviewAngiology2026

Vicious Circle With Venous Hypertension, Irregular Flow, Pathological Venous Wall Remodeling, and Valve Destruction in Chronic Venous Disease: A Review.

Gyorgy L Nadasy, Bernadett B Patai, Andrea A Molnar, Judit R Hetthessy, Anna-Maria Tokes, Zoltan Varady, Gabriella Dornyei

Abstract readReview
In one paragraph

Review in Angiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Ultrasound evaluation of the anatomy and hemodynamics of the Giacomini vein.Quantitative imaging in medicine and surgery · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gyorgy L NadasyDepartment of Physiology, Semmelweis University, Budapest, Hungary.ORCID 0000-0003-2057-2391
Bernadett B PataiDepartment of Traumatology, Military Hospital, Budapest, Hungary.ORCID 0000-0003-1631-1607
Andrea A MolnarDepartment of Cardiology, Semmelweis University, Budapest, Hungary.
Judit R HetthessyDepartment of Orthopedics, Semmelweis University, Budapest, Hungary.ORCID 0000-0001-8274-5257
Anna-Maria TokesDepartment of Pathology, Forensic and Insurance Medicine, Semmelweis University, Budapest, Hungary.
Zoltan VaradyVenenzentrum, Frankfurt a. M., Germany.
Gabriella DornyeiDepartment of Morphology and Physiology, Health Science Faculty, Semmelweis University, Budapest, Hungary.ORCID 0000-0001-7007-6252

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Substantial advances occurred in phlebological practice in the last two decades. With the use of modern diagnostic equipment, the patients' venous hemodynamics can be examined in detail in everyday practice. Application of venous segments for arterial bypasses motivated studies on the effect of hemodynamic load on the venous wall. New animal models have been developed to study hemodynamic effects on the venous system. In vivo and in vitro studies revealed cellular phase transitions of venous endothelial, smooth muscle, and fibroblastic cells and changes in connective tissue composition, under hemodynamic load and at different locations of the chronically diseased venous system. This review is an attempt to integrate our knowledge from epidemiology, paleoanthropology and anthropology, clinical and experimental hemodynamic studies, histology, cell physiology, cell pathology, and molecular biology on the complex

Indexed as

Vascular RemodelingVeinsVenous InsufficiencyVenous ValvesAnimalsChronic DiseaseHemodynamicsHumanscell pathologychronic venous diseasehemodynamicspathomechanismvaricosity

Identifiers

PMID38839285
PMCPMC12852497

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.