ArticleScience advances2024
Plasticity and lineage commitment of individual T
Abstract read
In one paragraph
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Shenling Baizhu Powder Alleviated Lung Damage and Enhanced Immunoregulatory Activity in Mice with Non-Tuberculosis Mycobacterial Lung Disease.Chinese journal of integrative medicine · 2026Article
- Alternative Splicing: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets.MedComm · 2025Review
- Stable characteristics of intrapopulation heterogeneity in virus-specific Th1 cells during chronic viral challenge infection.bioRxiv : the preprint server for biology · 2025Article
- Dosing interval is a major factor determining the quality of T cells induced by SARS-CoV-2 mRNA and adenoviral vector vaccines.Science immunology · 2025Article
- IL-15 functionalized biomimetic hybrid mRNA vaccine for enhanced NSCLC immunotherapy via synergistic activation of T cells and NK cells.Materials today. Bio · 2025Article
- T-bet overexpression enhances CAR T cell effector functions and antigen sensitivity.Journal for immunotherapy of cancer · 2025Article
- Chronic Inflammation in Asthma: Looking Beyond the Th2 Cell.Immunological reviews · 2025Review
- Adenosine receptors on the immuno-oncology expressway: TIME, perspectives, and translation.Frontiers in immunology · 2025Review
- Deciphering the deterministic role of TCR signaling in T cell fate determination.Frontiers in immunology · 2025Review
- Hybrid regulatory T cells: camouflaged architects of tumor immunity.Frontiers in immunology · 2025Review
- Stable characteristics of intrapopulation heterogeneity in virus-specific Th1 cells during chronic viral challenge infection.Frontiers in immunology · 2025Article
- Multistability and predominant hybrid phenotypes in a four node mutually repressive network of Th1/Th2/Th17/Treg differentiation.NPJ systems biology and applications · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Ahmed N HegazyCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Medical Department of Gastroenterology, Infectious Diseases and Rheumatology, 12203 Berlin, Germany.ORCID 0000-0002-2946-8251
Caroline PeineCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, 10117 Berlin, Germany.ORCID 0000-0001-6267-3452
Dominik NiesenCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, 10117 Berlin, Germany.ORCID 0000-0003-3204-123X
Isabel PanseCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, 10117 Berlin, Germany.
Yevhen VainshteinGerman Cancer Research Center (DKFZ), Division of Theoretical Systems Biology, 69120 Heidelberg, Germany.ORCID 0000-0001-7944-8892
Christoph KommerGerman Cancer Research Center (DKFZ), Division of Theoretical Systems Biology, 69120 Heidelberg, Germany.
Qin ZhangGerman Cancer Research Center (DKFZ), Division of Theoretical Systems Biology, 69120 Heidelberg, Germany.ORCID 0009-0007-2569-5573
Tobias M BrunnerCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, 10117 Berlin, Germany.ORCID 0000-0002-5279-2391
Michael PeineCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, 10117 Berlin, Germany.ORCID 0000-0002-3959-8260
Anja FröhlichCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, 10117 Berlin, Germany.ORCID 0009-0008-2677-131X
Naveed IshaqueGerman Cancer Research Center (DKFZ), Division of Theoretical Systems Biology, 69120 Heidelberg, Germany.ORCID 0000-0002-8426-901X
Roman M MarekCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, 10117 Berlin, Germany.ORCID 0000-0002-5267-2787
Jinfang ZhuNational Institute of Allergy and Infectious Diseases, Laboratory of Immune System Biology, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-0117-4745
Thomas HöferGerman Cancer Research Center (DKFZ), Division of Theoretical Systems Biology, 69120 Heidelberg, Germany.ORCID 0000-0003-3560-8780
Max LöhningCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, 10117 Berlin, Germany.ORCID 0000-0001-6382-7281
Funding
Transcriptional Regulation of Immune Cell Development, Activation and FunctionsZIAAI001169 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ZHU, JINFANG · 2012 to 2025
$21.8MAbstract
T helper 1 (T
Indexed as
Cell DifferentiationCell LineageCell PlasticityT-Box Domain ProteinsTh1 CellsTh2 CellsAnimalsCytokinesGATA3 Transcription FactorGene Expression RegulationInterferon-gammaMiceT-bet Transcription FactorCytokinesGATA3 Transcription FactorInterferon-gammaT-bet Transcription FactorT-Box Domain Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.